摘要
存在低病毒血症(LLV)的HIV感染人群(PLWH)发生病毒学失败、异常免疫激活、HIV耐药突变、艾滋病和非艾滋病相关疾病及死亡的风险增高。目前,我国尚缺乏针对LLV管理的统一规范。中华医学会热带病与寄生虫病分会艾滋病学组、浙江省数理医学学会感染性疾病专业委员会及浙江省性病艾滋病防治协会艾滋病诊疗质控管理专业委员会基于我国PLWH临床管理现状,参考国内外相关指南、最新研究进展及专家建议,制定了《HIV感染人群低病毒血症管理专家共识(2025版)》,本文对此共识的要点做一解读。
People living with HIV(PLWH)experiencing low-level viremia(LLV)face increased risks of virologic failure,abnormal immune activation,HIV drug resistance mutations,AIDS-related and non-AIDS-related comorbidities,and mortality.Currently,standardized management guidelines specifically addressing LLV in the context of HIV care are lacking in China.To address this gap,the AIDS Committee,Chinese Society of Tropical Disease and Parasitology,Infectious Diseases Professional Committee of Zhejiang Society for Mathematical Medicine,and Committee of AIDS Diagnosis and Treatment Quality Control Management,Zhejiang Provincial STD/AIDS Prevention Association jointly formulated the Expert Consensus on the Management of Low-Level Viremia in People Living with HIV(2025 Edition).This consensus synthesizes domestic clinical practices,international guidelines,recent research advancements,and expert recommendations.This article provides a critical interpretation of the key recommendations outlined in the consensus.
作者
杨宗兴
师金川
Yang Zongxing;Shi Jinchuan(Second Department of Infectious Diseases,Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University,Hangzhou 310023,China)
出处
《中华临床感染病杂志(中英文)》
北大核心
2025年第2期92-95,共4页
Chinese Journal of Clinical Infectious Diseases
基金
国家重点研发计划项目(2023YFC2306703)
杭州市卫生科技计划项目(A20251320)。
