摘要
佐太是藏药中最具代表性的炮制品,具有治疗疾病、解毒、养生补养、增效等作用。佐太及其制剂成为了藏医临床解毒的核心药物。目前,对佐太的研究主要集中在炮制工艺的历史传承和安全性探索方面,而对其解毒功效的研究和确证工作相对较少。本文通过搜集与整理藏医药经典著作,系统梳理了佐太解毒的文献依据,考证了佐太解毒功效。依据藏医药“三胃火”学说、“七精三秽”学说、“味性化味”理论,结合毒对机体的作用及疗毒原则,应用藏医药药性分析方法,解析佐太炮制原料的“味性效”,探讨佐太解毒的藏医药原理。佐太五源以“水源”和“土源”为主,六味以“甘味”为主,十七效以“沉、钝、凉、腻、稳、软”为主,可消除“毒”的“轻、锐、热、细、晃、糙”等性能,以上药性能够治疗毒对机体作用时产生的隆病和赤巴病,使得体内“三胃火”“七精三秽”及“三因素”功能趋于平衡。此外,佐太原料还具有解毒、愈疮、治脑伤等本质功效,能够实现解毒的目的。本文初步明晰了佐太解毒的功效原理,为研究佐太解毒的有效性、作用机制和临床应用提供一定的理论参考。
Zuotai is the most representative prepared product in Tibetan medicine,with functions such as treating diseases,detoxification,nourishing health,and enhancing efficacy.Zuotai and its formulations has become the core medicines for detoxification in Tibetan medical practice.Currently,research on Zuotai mainly focuses on the historical inheritance of processing techniques and exploration of safety,with relatively less research and confirmation on its detoxification effects.This study systematically organized the literature basis for the detoxification efficacy of"Zuotai"by collecting and compiling classical works of Tibetan medicine.It examined the detoxification effects of Zuotai based on the Tibetan medical theories of"Three Stomach Fires","Seven Essences and Three Impurities",and"Ro Nus ZhurJes"combined with the principles of toxic effects on the body and detoxification treatment.Using Tibetan medicinal property analysis methods,the study interpretd the"taste,nature,and efficacy"of Zuotai's processing ingredients and explored the Tibetan medical principles behind Zuotai's detoxification.The five sources of Zuotai are primarily"water"and"earth,"with the six tastes dominated by"sweetness,"and the seventeen efficacies mainly characterized by"heavy,blunt,cool,oily,stable,and soft".These properties counteract the"light,sharp,hot,fine,unstable,and rough"characteristics of toxins,thereby treating diseases caused by toxins,such as"Lung"and"Tripa"disorders,and restoring balance to the"Three Stomach Fires","Seven Essences and Three Impurities",and"Three Humors".Additionally,the raw materials of Zuotai possess intrinsic properties of detoxification,wound healing,and treating brain injuries,achieving the purpose of detoxification.This study preliminarily clarified the efficacy principles of Zuotai's detoxification,providing a theoretical reference for further research on its effectiveness,mechanisms,and clinical applications.
作者
索南拉毛
豆改杰
扎西卓玛
周拉太
魏立新
李先加
周文斌
SONAM Lhamo;DUKAR Gyap;TASHI Dolma;ZHOU Latai;WEI Lixin;LI Xianjia;ZHOU Wenbin(Qinghai(Tso-Ngon)University Tibetan Medical College,Xining 810016,China;XiZang University of Tibetan Medicine,Lhasa 850007,China;Tibetan Hospital of Xinghai County,Xinghai County 813399,China;CAS Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology of Chinese Academy of Sciences,Xining 810001,China;Qinghai Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation,Northwest Institute of Plateau Biology of Chinese Academy of Sciences,Xining 810001,China;State Key Laboratory of Tibetan Medicine Research and Development,Xining 810016,China)
出处
《世界科学技术-中医药现代化》
北大核心
2025年第5期1343-1350,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家重点研发计划“中医药现代化”重点专项(2024YFC3505600):少数民族药炮制、配伍“减毒存效”理论机制阐释与评价技术研究,负责人:魏立新
青海省科学技术厅十大国家级科技创新平台培育建设项目-现代藏药创制全国重点实验室(ZYYSDPT-2024-03):藏药佐太解毒增效作用研究,负责人:周文斌。
