摘要
目的:分析利多卡因联合亚甲蓝在肛肠疾病患者术后镇痛中的应用效果。方法:选取2021年1月—2022年12月于浠水县总医院巴河分院行手术治疗的70例肛肠疾病患者开展研究,用随机数字表法分为两组,各35例。术后,两组均予以常规管理,对照组采用双氯芬酸钠进行镇痛,观察组采用利多卡因联合亚甲蓝进行镇痛。比较两组临床疗效。结果:术后2h、12h和48h,观察组活动状态、静息状态下的视觉模拟评分法评分均低于对照组(P<0.05)。术后即刻,两组肾上腺素(E)、去甲肾上腺素(NE)、皮质醇(Cor)水平比较,差异无统计学意义(P>0.05);术后1d,两组E、NE、Cor水平均高于术后即刻(P<0.05),但观察组低于对照组(P<0.001)。观察组术后首次排便时间、术后首次肛门排气时间和肠鸣音恢复时间均早于对照组,差异有统计学意义(P<0.001)。观察组并发症发生率低于对照组(P<0.001)。结论:利多卡因联合亚甲蓝在肛肠疾病患者术后镇痛中的应用效果显著,能有效缓解疼痛,减轻应激反应,缩短胃肠功能恢复时间,预防并发症。
Objective:To analyze the application effect of lidocaine combined with methylene blue in postoperative analgesia of patients with anorectal diseases.Methods:A total of 70 patients with anorectal diseases who underwent surgery treatment in Bahe Branch of Xishui County General Hospital from January 2021 to December 2022 were included in the study.They were divided into two groups according to random number table method,with 35 cases in each group.After surgery,both groups received conventional management.The control group received analgesia using diclofenac sodium,and the observation group received analgesia using lidocaine and methylene blue.The clinical efficacy of the two groups was compared.Results:At 2 h,12 h and 48 h after surgery,the visual analogue scale scores under activity state and resting state in the observation group were lower than those in the control group(P<0.05).Immediately after surgery,there was no statistically significant difference in the levels of epinephrine(E),norepinephrine(NE),and cortisol(Cor)between the two groups(P>0.05).On 1 d after surgery,the levels of E,NE,and Cor in both groups were higher than those immediately after surgery(P<0.05),but the levels in the observation group were lower than those in the control group(P<0.001).The time of postoperative first defecation,the time of postoperative first anal exhaust,and the time of bowel sound recovery in the observation group were earlier than those in the control group,with a statistically significant difference(P<0.001).The incidence of complications in the observation group was lower than that in the control group(P<0.001).Conclusion:The application of lidocaine combined with methylene blue has significant effects in postoperative analgesia of patients with anorectal diseases,and can effectively alleviate pain,relieve stress reactions,shorten the recovery time of gastrointestinal function,and prevent complications.
作者
夏国良
Xia Guoliang(Comprehensive Ward,Bahe Branch of Xishui County General Hospital,Huanggang 438200,Hubei Province,China)
出处
《中国社区医师》
2025年第15期13-15,共3页
Chinese Community Doctors
关键词
利多卡因
亚甲蓝
肛肠疾病
手术
疼痛
应激反应
Lidocaine
Methylene blue
Anorectal diseases
Surgery
Pain
Stress reaction
