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HPV检测联合阴道镜下宫颈活检对于宫颈上皮内肿瘤的诊断分析 被引量:4

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摘要 目的探讨人乳头瘤病毒(HPV)检测联合阴道镜下宫颈活检对于宫颈上皮内肿瘤的临床诊断分析.方法选取2017年7月至2018年12月在本院接受HPV检测,结果提示阳性(16、18分型阳性或其他分型多次阳性)行阴道镜下活检,556例患者为观察对象,对其临床检查结果进行回顾性分析.结果经阴道镜联合宫颈活检后,发现HPV阳性患者最终诊断为宫颈上皮内肿瘤的占84.5%.结论HPV检测联合阴道镜下宫颈活检对于诊断宫颈上皮内肿瘤有较高的价值,并且有重要的临床意义,值得临床推广普及. Objective To investigate the effectiveness of combining HPV detection with colposcopy cervical biopsy in the clinical diagnosis of cervical intraepithelial neoplasia.Methods Among subjects who took HPV test in our Hospital between July 2017 and December 2018,those tested positive either in a single test for HPV subtypes 16 and/or 18,or in multiple tests for other subtypes were subject tofurther colposcopy biopsy.A total of 556 patients took the combined procedures.The clinical results of these patients were analyzed retrospectively.Results 84.5% of HPV-positive patients were diagnosed to have cervical intraepithelial tumors after colposcopy combined with cervical biopsy.Conclusion HPV detection combined with colposcopy cervical biopsy is effective in the diagnosis of cervical intraepithelial neoplasia.This study provides evidence for the clinical significance of this combined approach,it is worthy of clinical promotion.
出处 《浙江临床医学》 2020年第4期558-559,共2页 Zhejiang Clinical Medical Journal
关键词 HPV检测 阴道镜活检 宫颈上皮内肿瘤 HPV test Colposcopy biopsy Cervical intraepithelial neoplasia
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  • 1Moyer AV, Le Fevre ML, Siu AL, et al. Screening for cervical cancer: U. S. Preventive services task force recommendation statement [J]. Ann Intern Med. 2012,156(12) :880 -891.
  • 2Petry KU. Management options for cervical intraepithelial neoplasia [J]. Best PractRes Clin Obstet Gynaecol,2011,25 (5) :641 -651.
  • 3Santesso N, Schunemann H, Blumenthal P, et al. World health organization guidelines: use of cryotherapy for cervical intraepithelial neoplasia [J]. Int J Gynaecol Obstet, 2012,118 ( 2 ) : 97 - 102.
  • 4Jakobsson M, Gissler M, Paavonen J, et al. Loop electrosurgical excision procedure and the risk for preterm birth [J]. Obstet Gynecol, 2009,114(3) :504 -510.
  • 5Kyrgiou M, Koliopoulos G, Martin HP, et al. Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions : systematic review and meta-analysis [ J ]. Lancet, 2006, 367 (9509) :489 -498.
  • 6Leiman G, Harrison NA, Rubin A. Pregnancy following conization of the cervix:complications related to cone size [ J ]. Am J Obstet Gynecol, 1980,136 ( 1 ) : 14 - 18.
  • 7Kashyap V,Hedau S.Value of high-risk human papillomavirus 16deoxyribonucleic acid testing with cytological entities in peri and postmenopausal women[J].J Cytol,2013,30(3):190-194.
  • 8Agodi A,Barchitta M,La Rosa N.Human papillomavirus infection:low-risk and high-risk genotypes in women in Catania,Sicily[J].Int J Gynecol Cancer,2009,19(6):1094-1098.
  • 9Gupta S,Sodhani P.Reducing"atypical squamous cells"overdiagnosis on cervicovaginal smears by diligent cytology screening[J].Diagn Cytopathol,2012,40(9):764-769.
  • 10Johnston EI,Logani S.Cytologic diagnosis of atypical squamous cells of undetermined significance in perimenopausaland postmenopausal women:lessons learned from human papillomavirus DNA testing[J].Cancer,2007,111(3):160-165.

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