摘要
目的研究早期高血压性脑出血血肿扩大的相关因素及其预测价值。方法回顾性分析220例高血压脑出血患者的临床资料。按照患者入院时的CT结果分为血肿扩大组(120例)和血肿稳定组(100例),比较两组患者的相关临床及实验室、影像学检查指标。结果两组患者的入院收缩压、舒张压、活化部分凝血活酶时间(APTT)、血白细胞(WBC)数、CT血肿量、血丙氨酸氨基转移酶(alanine aminotransferase,ALT)水平、入院格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分、首次检查CT时间、血肿部位、是否破入脑室及血肿形态比较,差异均有统计学意义(P<0.005-0.001)。多元Logistic回归分析显示,入院收缩压、GCS评分、血肿部位及血ALT水平为早期高血压脑出血患者血肿扩大的独立危险因素。结论早期高血压性脑出血患者的入院收缩压、GCS评分、血肿部位及血ALT水平是血肿扩大的独立危险因素;并且联合上述指标对血肿扩大的预测价值更高。
Objective To analyze the related factors of early hematoma enlargement in patients with hypertensive intracerebral hemorrhage and the predictive value of vital signs combined with biochemical indicators.Methods The clinical data of 220 patients with hypertensive intracerebral hemorrhage who were treated in a neurovascular surgery department from January 2017 to June 2018 were ananlyzed retrospectively.The patients were divided into observation group(n=120,hematoma enlargement)and control group(n=100,hematoma stable)according to the brain CT results.The general clinical data,relevant laboratory test results and imaging findings were compared between the two groups.Results The differences in systolic blood pressure,admission diastolic blood pressure,activated partial thromboplastin time(APTT)expression,white blood cell(WBC)expression,CT hematoma,alanine aminotransferase expression,admission GCS score,the first CT time,hematoma location,rupture into the ventricle or not,and hematoma morphology between the two groups were statistically significant(P<0.005-0.001).Logistic multiple regression analysis showed the systolic blood pressure,GCS score,hematoma site and alanine aminotransferase were independent risk factors for hematoma enlargement in patients with early hypertensive intracerebral hemorrhage.Conclusions Systolic blood pressure,GCS score,blood glucose,hematoma site and alanine aminotransferase are the independent risk factors for hematoma enlargement in patients with early hypertensive cerebral hemorrhage.Combined with the above indicators,it can predict the patients with early hypertensive cerebral hemorrhage.
作者
朱贤龙
施辉
明圆圆
樊拥军
陈岩
邵世珂
仲崇佩
ZHU Xian-long;SHI Hui;MING Yuan-yuan(Department of Neurosurgery,Second People's Hospital of Lianyungang City,Lianyungang 222000,China)
出处
《临床神经外科杂志》
CAS
2019年第6期546-549,共4页
Journal of Clinical Neurosurgery
关键词
高血压性脑出血
血肿扩大
生命体征联合生化指标
预测
hypertensive cerebral hemorrhage
hematoma enlargement
vital signs combined with biochemical indicators
prediction
