期刊文献+

人类免疫缺陷病毒感染合并冠心病患者的临床特征分析

Clinical Characteristics of Patients with Human Immunodeficiency Virus Infection Complicated with Coronary Heart Disease
暂未订购
导出
摘要 目的分析合并人类免疫缺陷病毒(HIV)感染的冠心病患者临床特征变化情况。方法选取2016年3月-2018年3月,于广州市第八人民医院心内科、感染科住院且诊断冠心病合并HIV感染者16例。根据入选患者性别、年龄(±1岁)选择16位非HIV感染的冠心病者为对照组。所有入选者住院期间均行冠状动脉造影检查明确冠心病诊断,且行心脏彩超检查。分析比较两组患者各项临床指标。结果两组患者间血红蛋白计数有差别(P <0. 05)。两组间比较在前降支及右冠状动脉血管狭窄程度上差别有统计差异(P <0. 05),回旋支血管病变程度差异无统计学意义。两组患者在冠脉血管病变支数上无差别,但合并HIV感染患者多支血管病变例数更多。合并HIV感染的冠心病者左室收缩功能受损。结论合并HIV感染的冠心病患者血红蛋白数更低,前降支及右冠状动脉血管的狭窄程度更严重,左室收缩功能下降。 Objective To analyze the clinical characteristics of patients with coronary heart disease complicated with HIV infection. Methods From March 2016 to March 2018,16 patients with coronary heart disease and HIV infection were hospitalized in the Department of Cardiology and Infectious Diseases of the Eighth People’s Hospital of Guangzhou. Sixteen non-HIV-infected patients with coronary heart disease were selected as the control group according to their gender and age( ± 1 years). All patients underwent coronary angiography during hospitalization to confirm the diagnosis of coronary heart disease,and underwent color Doppler echocardiography. To analyze and compare the clinical indicators of patients with coronary heart disease complicated with HIV infection and non-HIV infection. Results There was a difference in hemoglobin count between the two groups( P < 0. 05). There were statistical differences in the degree of stenosis of the anterior descending branch and right coronary artery between the two groups( P < 0. 05),and there was no significant difference in the degree of atherosclerosis of the circumflex branch between the two groups. There was no difference in the number of coronary artery lesions between the two groups,but there were more cases of multi-vessel lesions in patients with HIV infection. Left ventricular systolic function was impaired in CHD patients with HIV infection. Conclusion Patients with coronary heart disease complicated with HIV infection had lower hemoglobin count and more severe stenosis of the anterior descending branch and right coronary artery,and left ventricular systolic function decreased.
作者 吕明芳 童裕维 李景隆 李莹莹 秦志慧 LV Mingfang;TONG Yuwei;LI Jinglong;LI Yingying;QIN Zhihui(The Eighth people' s hospital of Guangzhou , Guangzhou 510060, China)
出处 《现代医院》 2019年第6期891-894,共4页 Modern Hospitals
关键词 人类免疫缺陷病毒 冠心病 心脏功能 Human Immunodeficiency Virus Coronary Heart Disease Heart Function
  • 相关文献

参考文献9

二级参考文献116

  • 1王琼力,张凡萍,向燕萍,柳斌,许芳,胡小曼.社区控制高血压五年健康促进干预效果评价[J].中国全科医学,2007,10(6):501-503. 被引量:40
  • 2d'Arminio A,Sabin CA,Phillips AN,et al.Cardio-and cerebrovascular events in HIV-infected persons.AIDS,2004,18:1811-1817.
  • 3Matetzky S,Domingo M,Kar S,et al.Acute myocardial infarction in human immunodeficiency virus-infected patients.Arch Intern Med,2003,163:457-460.
  • 4Milei J,Grana D,Fernandez Alonso G,et al.Cardiac involvement in acquired immunodeficiency syndrome-a review to push action.The Committee for the Study of Cardiac Involvement in AIDS.Clin Cardiol,1998,21:465-472.
  • 5Duong M,Cottin Y,Piroth L,et al.Exercise stress testing for detection of silent myocardial ischemia in human immunodeficiency virus-infected patients receiving antiretroviral therapy.Clin Infect Dis.2002,34:523-528.
  • 6Bergersen BM,Sandvik L,Bruun JN,et al.Elevated Framingham risk score in HIV-positive patients on highly active antiretroviral therapy:results from a Norwegian study of 721 subjects.Eur J Clin MicrobiolInfect Dis,2004,23:625-630.
  • 7Mary-Krause M,Cotte L,Simon A,et al.Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men.AIDS,2003,17:2479-2486.
  • 8Henry K,Melroe H,Huebsch J,et al.Severe premature coronary artery disease with protease inhibitors.Lancet,1998,351:1328.
  • 9Flynn TE,Bricker LA.Myocardial infarction in HIV-infected men receiving protease inhibitors.Ann Intern Med,1999,131:548.
  • 10Carr A,Samaras K,Burton S,et al.A syndrome of peripheral lipodystrophy,hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitos.AIDS,1998,12:F51-F58.

共引文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部