摘要
本文应用显微分光光度术测定了IC例浆液性囊腺瘤,10例浆液性交界,26例浆液性囊腺癌的细胞DNA平均含量,细胞核平均面积及>5C的非整倍体胞核百分比,三组间有显著差异,P<0.001.当肿瘤细胞DNA含量>3O任意单位,胞核平均面积>65,且>5C的非整倍体胞核数超过50%,并有>8C的胞核出现时应诊断为腺癌.
DNA contents in serous ovarian tumors of 46 cases were measured by microspeetro-photometry and compared with histological assessment of the same tumor. All. tumors had been histologically classified as serous ovarian cystadenoma in 10 cases, borderline serous cystadenoma in 11 cases and serous cystadenocarcinoma in 25 cases. The results showed that DNA contents in cytadenoma group were within 4c (23 arbitrary units), in the borderline group were from 4c to 5c, in the cystadenocarcinoma group, some DNA contents exceeded 8c, (p<0.001). The mean nuclear size cf above 3 groups were 46.74, 59.49, and 76.01 respectively, (p<0.001). of the 46 cases only one previously diagnosed borderline tumor was rccla-ssified as invasive carcinoma, we suggested that adenecarci-noma should be diagnosed in case of DNA contents above 30 arbitrary units, nuclear size above 65 and percentage of aneuploidy cells with DNA>5c above 50% accompanying with seme DNA>8c
出处
《重庆医科大学学报》
CAS
CSCD
1991年第1期41-45,共5页
Journal of Chongqing Medical University
关键词
卵巢肿瘤
分光光度术
DNA
诊断
DNA content
Microspectrophotometry: Ovarian tumor
