摘要
目的了解重庆地区健康体检人群中幽门螺旋杆菌(HP)的感染情况,为疾病的预防和治疗提供依据。方法选取2017年1～12月西南医院健康体检者27 662例为研究对象,采用免疫胶体金法进行HP感染检测,并对检测结果进行分析。结果 27 662例检测者中,HP感染率24.58%(6 798/27 662),其中男性感染率为25.80%(4 222/16 366)略高于女性的22.8%(2 576/11 296),差异有统计学意义(χ~2=121.54,P=0.000);按年龄不同分为<30岁组,30～45岁组,46～60岁组和>60岁组,HP感染率依次为14.31%,23.7%,28.29%和31.36%,随着年龄增长HP感染率呈现增高趋势,差异有统计学意义(χ~2=372.831,P=0.000);各组内不同性别之间的HP感染率比较,30～45岁组,男性HP感染率为25.04%,明显高于女性感染率21.61%,差异有统计学意义(χ~2=11.042,P=0.001),其余几组内男性与女性的HP感染率比较,差异均无统计学意义(χ~2=1.412,1.672,0.826,均P>0.05)。结论重庆地区体检人群HP感染率与年龄、性别有关,且随着年龄的增长HP感染率呈增高趋势。
Objective To understand the infection status of Helicobacter pylori（HP） in healthy population during regular checkup in Chongqing Area and provides the basis for the prevention and treatment of the disease. Methods 27 662 cases of health examination in Southwest Hospital ftom January to December 2017 were selected as the research subjects, the immu- nocolloid gold method was used to detect HP infection,and the results were analyzed. Results Among the 27 662 subjects, the positive rate of HP infection was 24.58% （6 798/27 662） ,and the positive rate of male infection was 25.80%（4 222/16 366）, slightly higher than the positive rate of female 22.8 % （2 576/11 296） , the difference was statistically significant （ 121.54, P=0. 000）. The HP positive rates were 14.31 %,23.7%,28.29% and 31.36% in the group of 〈30,30-45,46- 60 and 〉60, respectively, the difference was statistically significant （χ^2=372. 831, P=0. 000）. Compared with sex at the same age stage, in 30-45 year old group, the positive rate of male HP infection was 25.04% significantly higher than that of female 21.61% ,the difference was statistically significant （χ^2=11. 042, P〈0. 001） ,and there was no significant difference in the positive rate of HP infection between men and women in other groups, the difference wasn＇t statistically significant （χ^2=1. 412,1. 672,0. 826 ,all P〈0.05）. Conclusion HP infection rate was related to sex and age in the physical examination population in Chongqing, and the positive rate of HP infection was increasing with age.
作者
孟凡娜
孙丽
MENG Fan na;SUN Li(the First Affiliated Hospital of Army Medical University PLA,Chongqing 400038,China)
出处
《现代检验医学杂志》
CAS
2018年第5期121-122,125,共3页
Journal of Modern Laboratory Medicine
关键词
健康人群
幽门螺旋杆菌
感染率
healthy population
Helicobacter pylori
infection rate
