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p-STAT3/5在肝癌中低表达机制的研究

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摘要 目前,肝癌的发病机制尚不清楚,其发生发展伴随着多种信号转导机制参与。STAT3/5(signal transducer and activator of transcription,STAT)作为信号传导与转录活化因子,在癌症的发生过程中发挥关键作用。有研究表明,STAT3/5信号通路的持续活化被视为癌症发生的标志;但Schneller等的研究发现,Ca-STAT3磷酸化可抑制癌症的发生.
出处 《承德医学院学报》 2018年第2期170-171,共2页 Journal of Chengde Medical University
基金 河北省高校重点学科建设项目资助[冀教高(2013)4号病理生理学]
关键词 肝癌 STAT3 STAT5
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