摘要
为了探讨老年原发性高血压患者血压晨峰现象与靶器官损害之间的关系,选取2015年1月~2015年12月的298例原发性高血压住院患者,所有病例均行动态血压监测、血液检测及超声心动图、颈动脉超声检查。结果显示晨峰血压组患者总胆固醇、低密度脂蛋白胆固醇水平较非晨峰血压组显著升高,差异有统计学意义（P〈0.05）。晨峰组与非晨峰组相比,晨峰组24h动态收缩压、日间动态收缩压、夜间动态收缩压、24h动态脉压、日间动态脉压、夜间动态脉压、左室重量指数及颈动脉内膜中层厚度均显著高于非晨峰组,差异具有统计学意义（P〈0.05）。因此血总胆固醇、低密度脂蛋白胆固醇水平可能是晨峰高血压发生的危险因素,老年原发性高血压患者伴有晨峰现象与靶器官损害密切相关。
To explore the relationship between morning blood pressure surge and target organ damage in elderly patients with primary hypertension.To analyze the association of morning blood pressure surge and left ventricular hypertrophy（LVH）and carotid intima-media thickness（IMT）.The results show that the level of blood total cholesterol,Low density lipoprotein-cholesterol of morning blood pressure surge group is higher than the level of non-morning pressure surge group,the difference between the two groups was significant（P0.05）.In MBPS group,24 hambulatory systolic blood pressure（SBP）,daytime ambulatory SBP,nighttime ambulatory SBP,24 hambulatory pulse pressure（PP）,daytime ambulatory PP,nighttime ambulatory PP,Left ventricular mass index（LVMI）and IMT were all significantly higher than those in non-MBPS group（P0.05）.So TC and LDL-C are possibly risk factors of MBPS phenomenon.The MBPS phenomenon was closely related to the target organ damage in elderly patients with primary hypertension.
作者
姜娜
黄丽红
JIANG Na HUANG Li-hong.(Cardiac Function Room, the Second Hospital of Dalian Medical University, Dalian 116027, China)
出处
《医学与哲学（B）》
2016年第12期31-33,46,共4页
Medicine & Philosophy(B)
关键词
老年原发性高血压
24H动态血压监测
血压晨峰现象
靶器官损害
eldly primary hypertension
24hambulatory blood pressure monitor（ABPM）
morning blood pressure surge（MBPS）
target organ damage
