摘要
目的探讨2015年舟山某院就诊小儿人群EB病毒(epstein-barr virus,EBV)、巨细胞病毒(czytomegalovirus,CMV)、柯萨奇病毒(Coxsackievirus,Cox V)感染的分布特征。方法选取2015年1月-12月在本院门诊或住院小儿患者1 284例,抽取静脉血分离血清,采用化学发光法EBV VCA-Ig M、EBV EA-Ig A、EBV VCA-Ig A、CMV-Ig M,采用酶联免疫法检测Cox V-Ig M。结果总样本群中EBV VCA-Ig M检出阳性83例(6.46%),EBV EA-Ig A检出阳性23例(1.79%),EBV VCA-Ig A检出阳性52例(4.05%),CMV-Ig M检出阳性88例(6.85%),Cox V-Ig M检出阳性150例(11.68%)。4岁~7岁的Cox V-Ig M阳性率(15.86%)高于1岁~3岁组(10.56%)和8岁~12岁组(9.80%),差异有统计学意义(χ2值分别为5.95、3.95,P<0.05)。1岁~3岁组男性EBV VCA-Ig M阳性率(8.14%)高于女性(4.89%),差异有统计学意义(χ2=6.83,P<0.01)。结论应加强本地区4岁~7岁患儿的Cox V-Ig M及1岁~3岁组的男性患儿EBV VCA-Ig M的监测。
Objective To investigate the distribution of Epstein -Barr virus （ EBV）, cytomegalovirus （ CMV）, Coxsackie virus （Coxv） in children in a hospital of Zhoushan in 2015. Methods 1 284 cases of children inpatients and outpatients were select- ed from January to December in 2015, and their peripheral blood were collected. Serum levels of EBV VCA - IgM, EBV EA - IgA, EBV VCA - IgA, CMV - IgM were detected by chemiluminescence, and CoxV - IgM was detected by euzymelinked immu- nosorbent assay（ELISA）. Results In the total samples, EBV VCA - IgM was positive in 83 cases （6.46%）, EBV EA -IgA was positive in 23 cases（ 1.79% ） , EBV VCA - IgA was positive in 52 cases（4.05% ） , CMV - IgM was positive in 88 cases （6.85%）, CoxV - IgM was positive in 150 cases（ 11.68% ）. Positive rates of CoxV - IgM in 4 -7 year group（ 15.86% ） was significantly higher than 1 -3 year group （ 10.56% ） and 8 - 12 year group （9.80%）, with the differences statistically signifi- cant（χ2 =5.95, 3.95, P〈0.05）. In 1 -3 years old group, positive rate of EBV VCA -IgM in male（8.14% ） was signifi- cantly higher than female （4.89%）, with the differences statistically χ 2 = 6.83 P 〈 0. . slgmficant（X , 01 ） Conclusion Monito- ring enhancement of CoxV - IgM and EBV VCA - IgM should be performed for children in 4 - 7 year and male children in 1 - 3 year, respectively.
作者
叶吉波
YE Ji - bo(Putuo Hospital of Zhejiang, Zhoushan , Zhejiang 316021, China)
出处
《中国卫生检验杂志》
CAS
2017年第1期138-140,共3页
Chinese Journal of Health Laboratory Technology
