摘要
目的探析胆石症患者血清癌胚抗原(CEA)以及糖类抗原19-9(CA19-9)表达的临床价值。方法分析2011年2月至2015年2月在我院接受治疗的98例胆石症患者(根据术前血清CEA、CA19-9的表达水平分为正常组52例和上升组46例)和44例腹股沟疝患者(对照组)的临床资料。检测受试者血清CEA、CA19-9及炎症因子的表达水平并进行比较,分析其在治疗胆石症患者中的重要作用。结果正常组与对照组间CEA、CA19-9及炎症因子的比较无统计学差异(P>0.05),而上升组患者的CEA、CA19-9及炎症因子均高于对照组,且差异具有统计学意义(P<0.05);术后与术前相比,正常组CEA、CA19-9及炎症因子的表达水平无统计学差异(P>0.05),而上升组的患者则明显降低,差异具有统计学意义(P<0.05)。结论胆石症患者中血清CEA、CA19-9的表达水平与胆道炎症有着一定的联系,胆道炎症较为严重时患者血清CEA、CA19-9表达水平上升。
Objective Our retrospective study was aimed to analyze the clinical value of serum CEA and CA19-9 in patients with cholelithiasis. Methods The clinical data of 98 patients with cholelithiasis and 44 patients with inguinal hernia received treatment in our hospital from February 2011 to February 2015 were retrospectively analyzed. The expressive levels of CEA and CA19-9 of the patients were detected and compared. The important roles of CEA and CA19-9 in the patients with cholelithiasis were analyzed. Results The levels of CEA,CA19-9and inflammatory factors in normal group and control group had no statistical differences（ P〈0. 05）. The levels of CEA,CA19-9 and inflammatory factors in rising group were higher than those in control group（ P〉0. 05）. The levels of CEA,CA19-9,inflammatory factors before and after the treatment had no statistical differences（ P〉0. 05）,but the levels of CEA,CA19-9,inflammatory factors in rising group were obviously decreased（ P〈0. 05）. Conclusion The levels of CEA and CA19-9 in patients with cholelithiasis had correlation with inflammation of biliary tract,which will increased by severe choleithiasis.
出处
《局解手术学杂志》
2016年第4期283-285,共3页
Journal of Regional Anatomy and Operative Surgery
关键词
癌胚抗原
糖类抗原19-9
胆石症
carcinoembryonic antigen
carbohydrate antigen 19-9
cholelithiasis
