摘要
生物钟现象存在于几乎所有生命体中,对多种生理活动和生物行为产生影响。除了中枢神经系统外,生物钟基因还广泛表达于包括睾丸在内的多种外周组织当中,提示其在男性生殖中具有重要功能。生物钟失调乃至于单个生物钟基因的缺失或突变,不仅会对生命体的行为活动产生影响,还可能对其生殖能力造成损害。近年来,男性生殖健康的问题越来越受到社会的关注,深入研究生物钟与男性生殖之间的关系,具有重要的研究意义和广泛的应用前景。
The circadian rhythm is involved in a variety of physiological and behavioral activities of almost all organisms. Clock genes are widely expressed not only in the central nervous system but also in many peripheral tissues including testis, suggesting that they may play important roles in male reproduction. Disorders of circadian rhythm, as well as deficiencies or mutations in single clock genes, may impair male reproductive functions. Male reproductive health has been paid great attention to in modern societies, it is certainly time to consider seriously the relationship between circadian rhythm and male reproduction.
出处
《生命科学》
CSCD
2015年第11期1462-1468,共7页
Chinese Bulletin of Life Sciences
基金
国家重点基础研究发展计划("973"项目)(2012CB947600)
国家自然科学基金项目(31070676
90919006
31571381)
关键词
生物钟
男性生殖
褪黑素
5-羟色胺
circadian rhythm
male reproduction
melatonin
serotonin
