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隐匿性乳腺癌10例诊治体会 被引量:2

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摘要 目的:分析隐匿性乳腺癌(OBC )诊断、治疗、预后情况,总结其诊治经验。方法:回顾分析我院2004年10月-2013年10月收治的10例OBC患者资料。结果:本组患者均以腋窝肿大淋巴结为首发症状,病理证实为转移腺癌。其中7例行乳癌改良根治术,2例行保留乳腺的腋窝淋巴结清扫术,1例仅行腋下肿块切除术。本组10例患者均获随访,随访时间12~108个月。9例进一步手术患者中1例术后36个月死于肺转移、脑转移。1例术后局部复发,并带瘤生存。其中1例未接受进一步治疗的患者于确诊后22个月因浸润性导管癌行乳癌改良根治术,已存活3年,其余患者均无瘤生存5年以上。结论:以腋下淋巴结肿大为首发症状,应高度警惕OBC可能,需行病理活检。治疗宜选择改良根治术或保乳术联合腋窝淋巴结清扫后全乳放疗,并辅以必要的化疗、内分泌治疗及可能的靶向治疗。
作者 秦宗阁
出处 《医学理论与实践》 2014年第21期2883-2884,共2页 The Journal of Medical Theory and Practice
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  • 1徐金刚,商谦.乳腺内成堆钙化的探讨[J].中华放射学杂志,1989,23(4):198-200. 被引量:9
  • 2Tench DW, Page DL. The unknown primary presenting with axillary lymphadenopathy [ M ]//Bland KI, Copeland EM, editors. The breast:Comprehensive management of benign and malignant diseases. Vol2.2nd ed. Philadelphia: W. B. Saunders, 1998:1447 - 1452.
  • 3Orel SG, Hochman MG,Schnall MD, et al. High-resolution MR imaging of the breast: clinical context[ J ]. RadioGraphies, 1996, 16(6) :1385 - 1401.
  • 4Lehman CD, Gatsonis C, Kuhl CK, et al. MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer[J]. N Engl J Med,2007,356(13) :1295 -1303.
  • 5Olson JA Jr,Morris EA,Van Zee KJ,et al. Magnetic resonance imaging facilitates breast conservation for occult breast cancer [J]. Ann Surg Oncol,2000,7(6) :411 -415.
  • 6Schwartz GF,Hortobagyi GN. Proceedings of the consensus conference on neoadjuvant chemotherapy in carcinoma of the breast, April 26 - 28,2003, Philadelphia, Pennsylvania [ J ]. Cancer, 2004,100(12) :2512 -2532.
  • 7Vlastos G,Jean ME,Mirza AN,et al. Feasibility of breast preservation in the treatment of occult primary carcinoma presenting with axillary metastasis [ J ]. Ann Surg Oncol,2001,8 (5) :425 - 431.
  • 8Merson M, Andreola S, Galimberti V, et al. Breast carcinoma presenting as axillary metastases without evidence of a primary tumor[J]. Cancer,1992,70(2) :504 -508.
  • 9Varadarajan R, Edge SB, Yu J, et al. Prognosis of Occult Breast Carcinoma Presenting as Isolated Axillary Nodal Metastasis [ J ]. Oncology,2007,71 (5 - 6 ) :456 - 459.
  • 10Medina-Franco H,Urist MM. Occult breast carcinoma presenting with axillary lymph node metastases [ J ]. Rev Invest Clin ,2002, 54 ( 3 ) :204 - 208.

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  • 1牛昀,范宇,傅西林.隐性乳腺癌的全乳腺次连续大切片检查[J].中华肿瘤杂志,1995,17(4):298-300. 被引量:34
  • 2蔡海峰,赵刚,潘惠承.新辅助化疗在隐匿性乳腺癌中的应用[J].中国综合临床,2006,22(6):538-539. 被引量:4
  • 3Halsted WS. The results of radical operation for the cure of car- cinoma of the breast[J]. AnnSurg,1907,46:1-19.
  • 4Llawes D, Neville .AM, Cote RI. Detection of occult metastasis in pa- tients with breast cancer[J]. Semin Surg Oncol, 2010,20 (4) : 312.
  • 5Walter B. Not every form of breast cancer can be demarcated with MRI[J]. Radiology, 2010,50 (10) : 843-844.
  • 6Hr SM, Cho DH, Lee SK, et al. Occult breast cancers manifes- ting as axillary lymph node metastasis in men: a two-case report [J]. J Breast Cancer, 2012, 3(15):359-363.
  • 7Gonzalez-Perez LM, lnfante-Cossio P, Crespo-Torres S, et al. Man- diblar metastases as first clinical sign of an occult male breast cancer [J]. Int J Oral Maxillofac Srg, 2012,1(?(41) :1211-1214.
  • 8He M, Tang LC, Yu KD, et al. Treatment outcomes and unfa- vorable prognostic factors in patients with occult breast cancer [J]. EurJ Surg Oncol, 2012, 11(38) :1022-1028.
  • 9Yang TJ,YangQ, Haffty BG,et al. Prognosis for mammograph- ically occult, early-stage breast cancer patients treated with breast-conservation therapy[J]. Int J Radiat Oncol Biol Phys, 2010,76(1):79-84.
  • 10Montagna E, Bagnardi V, Rotmensz N, et al. Immnohistochemical ly defined subtypes and outcome in occult breast carcinoma with axil lary presentation[J]. Breast Cancer Res Treat, 2011, 129 (3) : 867-875.

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