摘要
通过对检测幽门螺杆菌 (Hp)的两种方法 (PCR和快速尿素酶试验 )进行了比较 ,分析了各自的优缺点。应用以上两种方法对 76例消化道疾病患者的胃黏膜标本进行幽门螺杆菌检测 ,两法阳性者认为有 Hp感染。PCR的检出率为 6 8.4% ,快速尿素酶的检出率为 71.1% ,两者的敏感性均为 10 0 % ,特异性分别为 96 %和 88% ,两种检测方法无显著性差异 ;慢性浅表性胃炎、慢性萎缩性胃炎、消化性溃疡 Hp的感染率分别为 71.1%、6 1.3%、81.8%。结果表明 :HP感染与消化性疾病密切相关 ;两种方法都是检测 Hp感染的有效方法 。
This paper compares and analyzes the advantages and disadvantages of the two methods, PCR Method and rapid urease test (RUT), for the detection of helicobacter pylori (Hp). With the two methods, gastric mucosa samples from 76 patients with diseases of digestive tract were examined in search of helicobacter pylori. All the positive results, either from PCR or RUT, were regarded as infection caused by Hp. The detectable rate of PCR was 68.4 %, the detectable rate of RUT was 71.1 %. The susceptibility of the both methods to Hp was 100 %. The specificity of PCR or RUT was 96 % and 88 % respectively. The detected results with PCR differed insignificantly from those with RUT. The infectious rates of chronic superficial gastritis, chronic atrophic gastritis and peptic ulcer caused by Hp were 71.1 % , 61.3 % and 81.8 % respectively. In conclusion, Hp infection is closely linked to peptic diseases; both PCR and RUT are effective methods to detect Hp, which can be chosen for clinically according to hospital conditions.
出处
《实用医技杂志》
2002年第2期89-90,共2页
Journal of Practical Medical Techniques
