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低剂量X射线照射诱导HeLa细胞存活的兴奋效应及适应性反应 被引量:1

Hormesis and adaptive response of survival in HeLa cells induced by low dose X-ray irradiation
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摘要 采用集落形成法观察了低剂量X射线照射HeLa细胞的存活率。结果表明 ,小于 0 .5Gy的X射线照射细胞的存活率高于对照 ,得到了HeLa细胞存活的“兴奋效应” ,而且在 0 .2 5Gy附近这种效应更为明显 ;低剂量D1(0 .0 5、0 .75Gy)的预照射降低了随后攻击剂量D2 对细胞的损伤程度 ,反映出低剂量照射可诱发细胞存活的“适应性反应”。 The survival fraction in HeLa cells irradiated by low dose X-rays was observed using clone method. The results showed that the survival fraction in the cells irradiated by less than 0.5Gy X-rays was higher than control, ”hormesis” of HeLa cell survival was obtained and was significant at doses near 0.25Gy; also, the damage degree of cells induced by the following irradiation was reduced because of pre-treating the cells with low dose D 1 of 0.05, 0.75Gy; it was found from above that ”adaptive response” of cell survival was induced by the low dose irradiation.
出处 《核技术》 CAS CSCD 北大核心 2002年第3期223-226,共4页 Nuclear Techniques
基金 中国科学院"西部之光"人才培养计划 (XB980 6 0 4 )资助
关键词 X射线 HELA细胞 存活率 兴奋效应 适应性反应 生物效应 肿瘤 放射剂量 低剂量辐射 X-rays, HeLa cells, Survival fraction, Hormesis, Adaptive response
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  • 1邢成,国外医学军事医学分册,1989年,6期,16页
  • 2沈----,生物化学杂志,1986年,2期,35页

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