摘要
创伤愈合时 ,周围神经释放的神经肽在神经系统与损伤组织之间起着重要信号介导作用。神经肽不仅参与启动愈合早期的神经源炎性反应 ,并且通过对免疫细胞、修复细胞以及对生长因子网络的作用 ,调控伤口愈合。调节周围神经功能或在伤口局部应用神经肽 ,可能成为促进伤口愈合的重要措施。
Neuropeptides released from peripheral nerve in wound healing exert important transduction signals between impaired tissue and nervous system. They not only partipate in initiate neurogenic inflammation at early wound healing, but also affect the function and proliferation of immunecells and repair cells, and growth factor network. Modulation of the peripheral nerve function or focal application of an appropriate neuropeptide to the wound may be acceptable as an important therapeutical strategy for prompting wound healing.
出处
《创伤外科杂志》
2002年第1期55-58,共4页
Journal of Traumatic Surgery
基金
国家重点基础研究发展规划专项经费资助项目(G1999054204)
关键词
创伤
伤口愈合
神经肽
trauma
wound healing
neuropeptide
