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子宫珠蛋白的结构与功能 被引量:1

Uteroglobin: Structure and Function
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摘要 子宫珠蛋白 (UG)是类固醇激素诱导的、进化保守的多功能蛋白 ,从其基因结构、蛋白质结构、分布调节、合成的机制及其功能等方面来看 ,UG通过其假定受体介导自分泌和旁分泌途径发挥作用 ,它可能属于细胞因子 /趋化因子家族 ,关于UG结构、调节和功能的阐明将为揭示人类一般疾病。 Uteroglobin (UG) is a steroid inducible, evolutionarily conserved, multifunctional protein. In terms of molecular structure, regulation and synthesis mechanism, UG, which mediated autocrine and paracrine via its putative receptor, was surmised to be a member of the novel cytokine/chemokine family.Clarification of the structure, regulation and function of UG would contribute to elucidating human common disease, exploring the mystery of embryo implantation and researching the mechanism of oncogenesis.
作者 张键 段恩奎
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2001年第5期627-630,共4页 Progress In Biochemistry and Biophysics
基金 国家重点基础研究专项 (G19990 5 5 90 3 ) 国家"九五"攀登计划 (970 2 110 19 3 ) 中国科学院"百人计划" 知识创新工程经费资助~~
关键词 子宫珠蛋白 细胞因子 胚胎植入 肿瘤发生 结构 功能 uteroglobin, cytokine, embryo implantation, oncogenesis
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参考文献5

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同被引文献12

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