摘要
通过对16例放射性肺损伤资料的总结,讨论了照射剂量、照射野面积等因素与肺放射性损伤的发生及时间的关系,分析了肺损伤X线改变的动态表现,认为:(1)放射性肺损伤与放疗剂量及照射野面积关系密切,照射野面积大,能产生肺损伤的剂量相对就小。(2)急性放射性肺损伤多在放疗后1个月内出现;慢性肺纤维化平均在放疗后4.23个月出现,半年内纤维化发生率约为85.7％。(3)肺损伤的临床表现与X线征象不平行,临床表现程度一般较X线征象轻。此外,依据放射性肺损伤的X线表现及动态发展,还对肺损伤与肿瘤的间质性肺转移、普通肺炎及肿瘤放疗后复发的鉴别诊断进行了分析。
Based on the data of pulmonary radiation injury in 16 cases, the relationship among the radiation dosage and field, the development and onset time of the pulmonary radiation injury were discussed, and the dynamic changes of pulmonary radiation injury in X-ray films were analysed. The author found that: (1) there was a close relationship between the develop- ment of radiation injury and radiation dosages and the size of radiation fields, i. e, for the large radiation field, a relatively small dosage was needed for developing radiation injury; (2)most of acute radiation injury of the lungs appeared within one month of postirradiation therapy, and the chronic pulmonary fibrosis emerged appeared at 4.23 months after radiation therapyin average, with a fibrosis rate of about 85.7% within a half year; (3) the clinical manifestations of pulmonary radiation injury were not parallel to the X-ray signs, namely the X-ray changes were more severe than clinical manifestations. On the basis of X-ray signs and the dynamic changes of pulmonary radiation injury, the differentiation of radiation injury from interstitial pulmonary metastasis, primary tumor, common pneumonia, and tumor recurrence after radiation therapy were discussed.
出处
《军事医学科学院院刊》
CSCD
北大核心
1992年第4期287-290,共4页
Bulletin of the Academy of Military Medical Sciences
关键词
放射损伤
肺
X线
radiation therapy
pulmonary radiation injury
pulmonary fibrosis
