摘要
目的观察地佐辛与芬太尼用于神经外科患者术后自控静脉镇痛的效果及不良反应。方法 80名行神经外科手术的患者被随机分成芬太尼镇痛组(Ⅰ组,n=40)和地佐辛镇痛组(Ⅱ组,n=40)。Ⅰ组PCIA采用芬太尼16μg/kg、雷莫司琼0.6mg;Ⅱ组PCIA采用地佐辛0.8mg/kg、雷莫司琼0.6mg。观察并记录两组患者使用PCIA后2、6、12、24、48小时镇痛、镇静效果及不良反应情况。结果两组患者镇痛镇静效果无统计学差异(P>0.05),不良反应发生率差异有统计学意义(P<0.05)。结论 0.8mg/kg的地佐辛可以安全有效的应用于神经外科患者术后自控静脉镇痛。
Objective To observe the analgesic effects and adverse reactions of dezocine or fentanyl for patient--controlled intravenous analgesia（PCIA） of military sursery. Methods 80 patients of military surgery under general anesthesia were randomly divided into fentanyl group（group I , n = 40）and dezocine group（ group II ,n = 40）. The PCIA solution contained fentanyl 16ug/kg and ramosetron 0. 6mg in group I while dezocine 0. 8mg/kg a and ramosetron 0. 6mg in group II. Results There were no significantly different on the analgesic effects （ P 〉 0.05 ） and significantly different on the adverse reactions （ P 〈 0. 05 ）. Conclusion Dezocine 0. 8mg/kg can be safe and effective application in neurosurgery patients with PCIA.
出处
《中国老年保健医学》
2014年第1期32-33,共2页
Chinese Journal of Geriatric Care
