摘要
氨基酸是典型的两性物质,其羧基质子化常数已有报道,文献结果大都由pH电位法得到,而对氨基酸光学异构体(D、L、DL)的对比研究甚少,为检验光学活性起源理论中提出的D与L分子间的能量差异,我们曾用微量量热技术观察了苯丙氨酸、亮氨酸。
The thermodynamic functions of protonation reactions of α-carboxyl group of twelvekinds of amino acids--alanine?valine, lysine, leucine, phenylalanine, methionine, trypto-phan, threonine, serine, arginine, glutamic acid and glycine, have been determined by titration calorimetry combined with computer fit program. The differences between△H, AG, lgK, △S of the protonation reactions of amino acids have been reported. By comparison with pH titration method, it is simple, rapid and would be obtained simultaneously the total thermodynamic functions-IgK, △H, △6G and △S.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1991年第11期1522-1523,共2页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
氨基酸
质子化
滴定量热法
Titration calorimetry, Arnino acid, Protonation reaction
