摘要
目的观察纳洛酮治疗老年慢性肺源性心脏病合并肺性脑病患者的临床疗效。方法选择2010年3月～2012年4月收治的90例老年慢性肺源性心脏病合并肺性脑病患者作为研究对象,应用随机数字表法将患者分作为对照组和研究组各45例,对照组患者采用常规治疗,研究组患者则在常规治疗的基础上给予纳洛酮治疗,比较两组患者的临床疗效。结果研究组的总有效率显著高于对照组,比较差异具有统计学意义(P<0.05)。治疗后两组血氧分压(PaO2)、二氧化碳分压(PaCO2)、动脉血氧饱和度(SaO2)均显著改善(P<0.01),研究组改善更为明显(P<0.01)。结论纳洛酮治疗老年慢性肺源性心脏病合并肺性脑病效果显著,值得临床推广使用。
Objective To observe the clinical efficacy of naloxone in treating elderly patients with chronic cor puhnonale and pulmonary encephalopathy. Methods 90 elderly patients with chronic cor pulmonale and pulmonary encephalopathy,who were admitted to hospital from March,2010 to April,2012 ,were selected as the research objects. They were divided into the control group and the study group with 45 cases in each group hy random number table. The control group were treated by routine therapy, based on which naloxone was added to the study group.Then, clini- cal efficacy of both groups were compared.Results The total effective rate of the study group was significantly higher than that of the control group, which indicated that the difference between the two groups was statistically significant （ P 〈0.05 ）.The partial pressure of oxygen in blood（ PaO2 ）, partial pressure of carbon dioxide（PaCO2 ）, arterial oxygen saturation（SaO2 ）of both groups were obviously improved （ P 〈 0.01）, but those of the study group improved more obviously（ P 〈0.01 ）.Conclusion Naloxone can effectly treat elderly patients with chronic cor pulmonale and pulmonary encephalopathy.h is worth clinical application and popularizing.
出处
《右江医学》
2013年第6期822-823,826,共3页
Chinese Youjiang Medical Journal
关键词
纳洛酮
慢性肺源性心脏病
肺性脑病
naloxone
chronic cot pulmonale
pulmonary encephalopathy
