摘要
目的 探讨应用自体骨髓经皮注射移植的方法治疗骨不连和骨折延迟愈合的疗效.方法 选择2001-2011年不同部位骨不连、骨折延迟愈合患者36例,在无菌条件下行自体髂骨骨髓穿刺抽吸,X线引导下经皮注射移植到患部,并配合外固定等治疗.每个部位注射2～3次,平均2.4次.每3～4周注射一次.结果 术后平均随访9个月.36例患者中治愈32例,失败4例并转其他治疗方法,无感染及并发症发生.结论 自体骨髓经皮注射移植是一种效果确切、简便易行、省钱微创的治疗方法,尤其适合全身或局部条件不宜复杂操作的骨不连和骨折延迟愈合患者.
Objective To observe the application of percutaneous autogenous bone marrow injection grafting for management of 36 cases with delayed unionor nonunion of fractures.Methods In the period from 2001 to 2011,36 patients with delayed and non-union of long bones were selected for bone marrow injection.The procedures were gone through in the operative theatre in which the bone marrow were aspirated from the anterior or posterior iliac crest and injected into the fracture site under fluoroscopic control.The optimal injection interval of a dose of 5：20 mL was 34 weeks and the injection required 2-3 times per week.Results During a mean follow up of 9 months,32 of the 36 cases were healed with the technique of marrow injection.The time to clinical and roentgen graphic union was 6 to 11 months after injection （averaged 9 months）.Four cases failed and chose other treatments.Generally,there was no infection or complications.Conclusion Bone marrow injection is as effective as past open autologous grafting but with considerably fewer disadvantages,and also it is a relatively simple and economic technique,especially for elderly and infirm patients with ununited bones or delayed bones.
出处
《实用临床医药杂志》
CAS
2013年第16期104-105,共2页
Journal of Clinical Medicine in Practice
关键词
骨不连
自体骨髓
移植
ununited
autogenous bone marrow
transplantation
