摘要
本文报告 195 9～ 1998年青海高原人与动物多房棘球绦虫感染情况的研究结果。共手术治疗泡型包虫病人111例 ;男性 73例 ,女性 38例 ;其中肝泡球蚴病 10 0例 ,肺泡球蚴病 2例 ,脑泡球蚴病 7例 ,脾泡球蚴病 2例。年龄17～ 74岁 ,成年人最为常见。牧民和农民最多见 ,其他职业少见。普查 370 2人 ,B超诊断为肝泡球蚴病者 2 3人( 0 .6 2 % ) ,EM1 8血清学阳性者 30人 ( 0 .81% ) ,两种方法均符合者 13人 ( 0 .35 % )。调查中间宿主 7种 ,在家养动物牦牛肝脏和肺脏及藏绵羊肝脏发现泡球蚴感染 ,感染率分别为 4.0 9% ( 18/ 384)和 5 .36 % ( 31/ 5 78) ;野生动物黑唇鼠兔的肝脏和肺脏及灰尾兔的肺脏发现泡球蚴的感染 ,其感染率分别为 3.45 % ( 11/ 319)和 12 .5 0 % ( 1/ 8)。调查终宿主 5种 ,在藏犬和藏狐肠内均证实多房棘球绦虫感染 ,其感染率分别为 5 .0 8% ( 3/ 5 9)和 33.33% ( 4/ 12 )。提示青海高原存在多房棘球绦虫的藏犬、藏狐 /黑唇鼠兔、灰尾兔和藏犬、藏狐 /牦牛。
This paper is dealing with the infection of larval and adult Echinococcus multilocularis in human and animals in Qinghai from 1959 to 1998. A total of 111 cases with alveolar echinococcosis had been treated by surgical operation during this period. Including 73 male and 38 female cases; 100 cases with hepatic alveolar echinococcosis, 2 cases with pulmonary alveolar echinococcosis, 2 cases with splenic alveolar echinococcosis and 7 cases with brain alveolar echinococcosis. The age range from 17 to 74 years old. The adult had more numbers than the youngster and the aged. Most of patients with this disease were herdsman and peasants. As a matter of fact,the numbers of cases with alveolar echinococcosis confirmed by surgical operation and pathological technique were fewer than that of the realistic cases with this disease, because of false diagnosis as liver cancer and death which due to so poor finance that can not be treated. A total of 3702 residents had been examined by BUltrasound and EM 18 immunoblot analysis during the later two years. 23 cases with hepatic alveolar echinococcosis had been confirmed by BUltrasound,and the numbers of patients with this disease was risen to 30 cases confirmed by EM 18 immunoblot analysis, but only 13 cases with this disease accorded with those confirmed by EM 18 immunoblot analysis. A total of 7 species of intermediate hosts including domestic animals and rodents had been investigated by killing them and made a examination of their livers,lungs and other organs in abdominal cavity by anatomical methods, 5.36%(31/578) Tibetansheep and 4.69%(18/384) Yaks(two major aboriginal domestic animals in this areas), 3.45%(11/319) Ochotona curzoniae and 12.50%(1/8) Lepus oiostolus(two major aboriginal wild rodents). A total of 5 species of definitive hosts had been investigated by shoot and their intestine were examined by anatomical methods. Meanwhile, the parasitic species from their intestine also was identical by morphological character. The adult parasite could been found in the intestine of 5.08%(3/59) Tibetandogs and 33.33%(4/12) Tibetanvixen(two major aboriginal carnivoyous animals). It is suggested that two lifecycle models of Echinococcus multilocularis including Tibetandog,Tibetanvixen(carnivore)/Ochotone curzoniae, Lepus oiostolus(rodents) lifecycle model and Tibetandog, Tibetanvixen(carnivore)/Yaks,Tibetansheep(domestic animal) lifecycle model could been comfirmed in this areas.
出处
《中国寄生虫病防治杂志》
CSCD
2000年第2期120-123,共4页
Chinese Journal of Parasitic Disease Control
基金
国家自然科学基金重点项目!(No.39730400)
美国 Thrasher Research Fund资助
关键词
青海
人
动物
多房棘球绦虫
感染
流行病学
Qinghai
human
animal
Echinococcus multilocularis
infection
