摘要
目的观察辛伐他汀治疗心律失常的临床疗效及意义。方法将江门市人民医院2008年3月～2012年3月收治的60例心律失常患者随机分为观察组与对照组,各30例。对照组使用美托洛尔进行治疗,12.5～25.0mg/次,2次/d,观察组在此基础上使用辛伐他汀进行治疗,每晚口服20mg。两组患者连续治疗3个月为1个疗程,对比两组患者临床治疗效果。结果观察组患者治疗总有效率(23/30,76.67%)明显高于对照组患者(14/30,46.67%),室性、房性期前收缩次数(1507±1042,1124±428)明显少于对照组(2943±2147,1927±1046),差异有统计学意义(P<0.05);两组患者均未发现严重不良反应,且不良反应率差异无统计学意义(P>0.05)。结论辛伐他汀能够有效改善心律失常患者临床症状,比美托洛尔有更为理想的临床疗效。
Objective To observe the curative effect and clinical significance of treatment of arrhythmias using simvastatin. Methods From March 2008 to March 2012,60 cases arrhythmia were randomLy divided into observation group and control group, control group patients used metoprolol for treatment, observation group patients were given simvastatin based on the control group.The curative effect of two groups were compared. Results The total effective rate in observation group was significantly higher than that of the control group, ventricular, atrial premature contraction was significantly less than that of the control group, the difference was statistically significant （ P 〈0.05）; two patients were found serious adverse reactions, and the adverse reaction rate was no significant difference （ P 〉0.05）. Conclusion Simvastatin in the treatment of patients with cardiac arrhythmias, can effectively improve the clinical symptoms, compared with the clinical curative effect of metoprolol for ideal.
出处
《当代医学》
2013年第12期152-153,共2页
Contemporary Medicine
