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右美托咪啶在经鼻纤维支气管镜气管插管中的应用 被引量:1

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摘要 目的观察右美托咪啶应用于经鼻纤维支气管镜气管插管的效果和安全性。方法选择择期行颈椎前路减压植骨内固定手术患者60例,随机分为右美托咪啶组(A组)和对照组(B组)各30例。A组微量泵静脉注入右美托咪啶后,右美托咪啶微量泵持续泵入维持;B组单次咪达唑仑及芬太尼缓慢静脉注射,丙泊酚微量泵持续泵入维持。采用Ramsay镇静程度评分法,待患者Ramsay评分≥4级时行纤维支气管镜引导保留呼吸经鼻气管插管。分别于麻醉诱导前(t1)、气管插管前(t2)、气管插管即刻(t3)、插管后1 min(t4)、插管后3 min(t5)观察患者生命体征,记录不良反应发生情况。结果 t3、t4时A组平均动脉压、心率与B组比较,差异有统计学意义(P<0.01)。结论右美托咪啶应用于经鼻纤维支气管镜气管插管时患者血流动力学稳定,无呼吸抑制,镇静效果确切,临床应用安全可行。
出处 《医药导报》 CAS 北大核心 2013年第2期188-189,共2页 Herald of Medicine
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