摘要
目的:探讨干扰素治疗手足口病的临床疗效。方法:将223例具有发热和皮疹的普通手足口病患儿随机分为治疗组112例和对照组111例,治疗组在对照组一般抗病毒治疗的基础上给予干扰素10万U/(kg·日),1次/日,连续应用5天,观察体温变化和皮疹消退情况。结果:治疗组疗效明显优于对照组,两组疗效比较,差异有统计学意义(P<0.01)。结论:干扰素治疗小儿手足口病疗效显著。
Objective：To explore clinical curative effect of interferon on treating Hand foot and mouth disease（HFMD）.Methods：Divided randomly 112 cases of 223 HFMD children into treatment group,and 24 into control group.Give treatment group more interferon（100000U/kg pre day,once a day,5 days of continuous application）,while both of them are treated with general anti-viral.Then check the changes of body temperature and rash subsided situation.Results：The treatment group is significantly better than the control group.The difference was statistically significant（P0.01）with comparison of two groups.Conclusion：The clinical curative effect of interferon on treating HFMD is distinct and it is worthy of clinical use.
关键词
干扰素
小儿
手足口病
疗效
Interferon
Child
Hand foot and mouth disease（HFMD）
Curative effect
