摘要
OBJECTIVE:To observe the therapeutic effect of percutaneous kyphoplasty(PKP) and oral Zishengukang(ZSGK) for the treatment of osteoporotic vertebral compression fractures(OVCFs).METHODS:Seventy patients were randomly divided into a control group(PKP group) and an experimental group(PKP plus ZSGK group).The 35 patients in the experimental group were prescribed 6 g oral ZSGK three times a day for 90 days after PKP.Visual analog pain scale(VAS),Oswestry functional score,vertebral height and Cobb's angle were recorded and compared before treatment and at one week,one month and three months after treatment.RESULTS:Vertebral height and Cobb's angle significantly improved and VAS and Oswestry functional score were significantly lower in both groups after PKP than pre-operatively(P<0.01).Three months after treatment,VAS and Oswestry functional score in the experimental group were lower than controls(P<0.05),even though vertebral height and Cobb's angle were comparable(P>0.05).CONCLUSION:PKP combined with oral ZSGK provide superior short-term and long-term symptom control after OVCF than PKP alone.
OBJECTIVE： To observe the therapeutic effect of percutaneous kyphoplasty （PKP） and oral Zishengukang （ZSGK） for the treatment of osteoporotic vertebral compression fractures （OVCFs）. METHODS： Seventy patients were randomly divid- ed into a control group （PKP group） and an experi- mental group （PKP plus ZSGK group）. The 35 pa- tients in the experimental group were prescribed 6 g oral ZSGK three times a day for 90 days after PKP. Visual analog pain scale （VAS）, Oswestry functional score, vertebral height and Cobb＇s angle were re- corded and compared before treatment and at one week, one month and three months after treat- ment. RESULTS： Vertebral height and Cobb＇s angle signifi- cantly improved and VAS and Oswestry functional score were significantly lower in both groups after PKP than pre-operatively （P〈0.01）. Three months after treatment, VAS and Oswestry functional score in the experimental group were lower than controls （P〈0.05）, even though vertebral height and Cobb＇s angle were comparable （P〉0.05）. CONCLUSION： PKP combined with oral ZSGK provide superior short-term and long-term symptom control after OVCF than PKP alone.
