摘要
目的 :探讨膀胱癌的发生与 P16基因缺失的关系。方法 :采用双重 PCR法对 31例膀胱癌组织中 P16基因进行检测。结果 :31例膀胱癌组织中有 7例存在 P16基因缺失 ,缺失率为 2 2 .6 %。结论
Purpose:To investigate the deletion of P16 g ene in the bladder cancer.Methods:The P16 gene was analysi s by duplex PCR in 31 bladder cancer tissue samples.Results:The gene deletions were found in seven samples.The deletion ratio of P16 gene was 22.6 per cent.Five cases had deletion in exon 2. One case had deletion in exon 1 and one had deletion in both exon 1 and exon 2.Conclusions:The results suggest that the deletion of P16 gene were associated with some bladder cancer.
出处
《临床泌尿外科杂志》
2000年第6期271-272,共2页
Journal of Clinical Urology
