摘要
目的:观察枯草杆菌二联活菌肠溶胶囊联合乳果糖治疗便秘型肠易激综合征(IBS)的疗效及安全性。方法:204例便秘型IBS患者随机分为4组,分别给予枯草杆菌二联活菌肠溶胶囊联合乳果糖(A组)、单纯枯草杆菌二联活菌肠溶胶囊(B组)、单纯乳果糖(C组)及酚酞片(D组)口服,4周后比较4组患者的疗效和症状改善情况及不良反应。结果:A组临床总有效率高于其他3组,且对患者症状改善情况优于其他3组,差异均有统计学意义(P<0.05)。结论:枯草杆菌二联活菌肠溶胶囊联合乳果糖治疗便秘型IBS,临床总有效率和总体症状改善率均较高,且安全性较好。
OBJECTIVE：To observe the clinical efficacy of bacillus subtilis and enterococcus faecium enteric-coated capsules combined with lactulose in the treatment of constipation type irritable bowel syndrome.METHODS：204 cases of constipation type irritable bowel syndrome were randomly divided into 4 groups.They were given bacillus subtilis and enterococcus faecium enteric-coated capsules combined with lactulose（group A）,bacillus subtilis and enterococcus faecium enteric-coated capsules alone（group B）,lactulose alone（group C） and phenolphthalein tablets（group D）,respectively.Therapeutic efficacies and symptom improvement of 4 groups were compared after 4 weeks.RESULTS：The totals effective rate of Bacillus subtilis and enterococcus faecium enteric-coated capsules combined with lactulose group was higher than other 3 groups,there was statistical significance（P0.05）;the improvement of the symptoms was better than other 3 groups,there was statistical significance（P0.05）.CONCLUSION：Bacillus subtilis and enterococcus faecium enteric-coated capsules combined with lactulose improve total symptom and effective in the treatment of constipation type irritable bowel syndrome.
出处
《中国药房》
CAS
CSCD
2012年第44期4174-4175,共2页
China Pharmacy
关键词
枯草杆菌二联活菌肠溶胶囊
乳果糖
便秘型
肠易激综合征
Bacillus subtilis and enterococcus faecium enteric-coated capsules
Lactulose
Constipation type
Irritable bowel syndrome
