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几丁糖预防肘关节粘连的临床研究 被引量:35

CL INICAL STUDY ON CHITOSAN FOR PREVENTION OF EL BOW ADHESION
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摘要 目的 研究医用几丁糖预防肘关节粘连的临床作用。方法 对 2 6例肘关节僵硬患者进行手术松解 ,其中 12例术后关节腔内涂布 2 %几丁糖 ,另 14例术后不用几丁糖作为对照组 ,观察术后肘关节伸屈活动度改善程度以评定疗效。结果  2 6例均获随访 ,随访时间 8~ 5 1个月 ,平均 2 4个月。几丁糖组术后肘关节平均活动度恢复到 92 .9°± 2 0 .9°,比术前增加 5 5 .0°± 15 .9°;对照组术后肘关节平均活动度恢复到 75 .4°± 17.5°,比术前增加38.2°± 11.9°。几丁糖组术后肘关节伸屈活动度增值明显大于对照组 ,有显著性差异 (P<0 .0 1)。结论 医用几丁糖具有减轻或预防肘关节松解术后再粘连的形成。 Objective To study the clinical effectof chitosan on prevention of elbow adhesion after elbow arthrolysis. Methods Twenty six patients with elbow ankylosis were performed elbow arthrolysis,which divided into two groups,in chitosan group,12 patients were injected 2 % chitosan into the elbow joint cavity,and no chi- tosan used in the other 14patients as control group. The average range of extension and flexion of elbow jointwas detected to evaluate the clinical results. Results All patients were followed up 8to 5 1months,averaged 2 4 months. In the chitosan group,the average range of extension and flexion of elbow joint was restored to 92 .9°± 2 0 .9°,with an average increase of 5 5 .0°± 15 .9° com pared with preoperation. In the control group,the average range of extension and flexion of elbow joint was restored to 75 .4°± 17.5°,with an average increase of 38.2°± 11.9°.The outcome showed significant difference between the chitosan group and the control group(P<0 .0 1) . Conclusion Chitosan can prevent or reduce elbow adhesion after elbow arthrolysis.
出处 《中国修复重建外科杂志》 CAS CSCD 2000年第2期80-82,共3页 Chinese Journal of Reparative and Reconstructive Surgery
基金 国家自然科学基金! ( 3 8970 714 )
关键词 关节粘连 几丁糖 预防 肘关节 Joint Adhesion Chitosan
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