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儿童体位性心动过速综合征的发病机制 被引量:11

Pathogenesis of Postural Orthostatic Tachycardia Syndrome in Children
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摘要 体位性心动过速综合征是一种与体位有明确关系的窦性心动过速,特征性临床表现为当患者体位由平卧位转为直立时,于10 min内心率增加≥30次.min-1,或心率最大值≥120次.min-1。体位性心动过速的发病机制目前尚未明了,可能主要与中心血容量改变、自主神经及肌肉泵功能障碍、血管内皮功能异常以及基因变异等有关。 Postural orthostatic tachycardia syndrome is a kind of nodal tachycardia which is definitely related to postural. It is defined as a sustained heart rate increase of≥ 30 times ·min^-1 or increase of heart rate to ≥ 120 times ·min^-1 within the first 10 min standing. Postural orthostatic tachyeardia syndrome is a clinical manifestation of multiple underlying mechanisms, such as the changes of central blood volume, dysautonomia, muscle pump dysfunction, endothelium function disorder of blood vessel, gene variation et al.
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2012年第7期540-542,共3页 Journal of Applied Clinical Pediatrics
基金 国家"十二.五"支撑计划(2012BA103B03) 北京市科技计划首都特色项目(D10100050010059)
关键词 体位性心动过速综合征 发病机制 儿童 postural orthostatic tachycardia syndrome pathogenesis child
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