摘要
目的探讨白细胞(WBC)、C反应蛋白(CRP)和葡萄糖(GLU)测定在手足口病患儿中的临床应用。方法 155例患儿入院时和治疗3d后分别检测全血WBC和血清CRP以及GLU。结果以CRP>10mg/L为阳性,WBC>11.0×109/L为阳性,GLU>6.11mmol/L为阳性,手足口病患儿CRP阳性率为48.4%,WBC阳性率为18.1%,GLU阳性率为6.5%。轻症组经治疗后CRP下降明显,治疗前后差异有统计学意义(P<0.01),而WBC和GLU变化无明显差异,然而重症组CRP、WBC和GLU治疗前后差异无统计学意义。结论 CRP是手足口病的早期诊断敏感而非特异的指标,外周血WBC是鉴定病情严重程度的重要指标,高血糖是病情危重的早期预警标志物之一。
Objective To study the changes of WBC and serum CRP,Glucose in the children with hand,foot and mouth disease（HFMD） and explore its clinical significance.Methods Whole blood white blood cell（WBC） count and the concentration of serum C-reactive protein（CRP） and glucose were examined in 155 cases with HFMD on admission and 3 days after treatment.Results The positive rates of WBC,CRP and Glucose were 18.1%,48.4% and 6.5% respectively in the HFMD group.The concentration of CRP decreased obviously and the value had statistical significance on admission and post-treatment in mild group,meanwhile,WBC and Glucose had no statistical significance.Additionally,all above markers,including CRP,WBC and Glu had no statistical significance on admission and post-treatment in severe group.Conclusion CRP is were sensitive rather than specific marker in the early diagnosis in children with HFMD,WBC is identified an important indicator of the severity of the illness,high blood glucose is one of the early warning markers on critical condition.
出处
《检验医学与临床》
CAS
2012年第6期689-690,共2页
Laboratory Medicine and Clinic
关键词
手足口病
C反应蛋白
血葡萄糖
白细胞计数
hand
foot and mouth disease
serum C-reactive protein
serum glucose
white blood cell count
