摘要
目的:观察抗毒补心胶囊治疗病毒性心肌炎的临床效果及其对机体的免疫调节作用。方法:60例病毒性心肌炎患者随机分为治疗组、对照组,治疗组口服抗毒补心胶囊治疗,4粒/次,4次/d,口服,对照组用常规西药治疗,静滴极化液:10%葡萄糖注射液500 mL+胰岛素8 U+10%氯化钾10 mL,每天1次;口服辅酶Q10 20 mg,维生素C片0.2 g,每天3次,疗程4周。2组均酌情使用一般抗心律失常药。分别观察其临床疗效,肌酸肌酶(CK)及其同工酶(CK-MB),白细胞介素(IL-2)及肿瘤坏死因子(TNF-α)的变化。结果:治疗组、对照组有效率分别为93.3%和76.7%,二者比较差异有统计学意义(P<0.05);治疗后,2组患者心肌酶、TNF-α及IL-2水平下降,治疗前后比较差异有统计学意义(P<0.05);治疗组与对照组相比,差异亦有统计学意义(P<0.05)。结论:抗毒补心胶囊治疗病毒性心肌炎效果较好,且可调节机体的免疫功能。
Objective： To observe the clinical efficiency and immunological regulation of Kangdu Buxin capsule in treatment of viral myocarditis.Method： Sixty patients with VMC were randomly divided into treatment group and control group,treatment group was treated with Kangdu Buxin capsule and control group was treated with conventional therapy for 4 weeks.Clinical efficiency and improvement of CK,CK-MB,TNF-α,IL-2 were observed.Result：The total effective rates of treatment and control group were 93.3% and 76.7% with significant difference（P〈0.05）.After treatment,the levels of CK,CK-MB,IL-2,TNF-α were decreased in two groups（P〈0.05）.Compared with control group,statistical difference was also observed（P〈0.05）.Conclusion： Kangdu Buxin capsule is effective in the treatment of viral myoearditis,and it also has a good regulation effect on the immune function.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第24期200-202,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
河北省唐山市科技研发重点支持项目(08360202A-5)
关键词
抗毒补心胶囊
病毒性心肌炎
疗效
免疫
Kangdu Buxin capsule
viral myocarditis
curative effects
immune
