摘要
目的对比观察3种不同方法检测幽门螺杆菌(Hp)的临床效果。方法对680例消化道科就诊的患者分别采用改良W-S银染法、快速尿素酶试验(RUT)、14 C-尿素呼气试验(14 C-UBT)检测Hp感染,比较其检测Hp感染的效果。结果改良W-S法的检出率为71.32%,显著高于RUT法和14 C-UBT法,差异有统计学意义(P<0.05);RUT法和14 C-UBT法的检出率比较,差异无统计学意义;改良W-S法的灵敏性、特异性和准确性分别为96.04%、100.00%和97.06%,均显著高于RUT法和14 C-UBT法,差异有统计学意义(P<0.05);而RUT法和14 C-UBT法之间比较差异无统计学意义。结论改良W-S法检测Hp感染具有很高的灵敏性、特异性以及准确性,而且操作方法简便,成本低廉,值得临床推广应用。
OBJECTIVE To compare the clinical efficacy of three different methods for the detection of helicobacter pylori（Hp）.METHODS A total of 680 patients with gastrointestinal symptoms received modified W-S silver staining,rapid urease test（RUT） and 14C-urea breath test（14C-UBT） for detection of Hp,the efficacy of them were compared.RESULTS The positive rate of modified W-S silver staining was 71.32% which was significantly higher than RUT and 14C-UBT,the difference was statistically significant（P〈0.05）;while there was no significant differenec between RUT and 14C-UBT;the sensitivity,specificity and accuracy rate of modified W-S silver staining were 96.04%,100% and 97.06% respectively and which were significantly higher than RUT and 14C-UBT,the difference was statistically significant（P〈0.05）;while there was no significant differenec between RUT and 14C-UBT.CONCLUSION Modified W-S silver staining for detection of Hp infection has high sensitivity,specificity and accuracy,which is convenient and low cost,so it is worthy of clinical application.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第17期3746-3747,共2页
Chinese Journal of Nosocomiology
基金
广西卫生厅自筹经费科研课题(Z2010222)
