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聚丙烯酰胺凝胶的组织相容性实验 被引量:13

Experiment of histocompatibility of polyacrylamide gel
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摘要 目的:对比研究国产及进口聚丙烯酰胺的组织相容性.方法:选用昆明小白鼠32只,随机分为3组4个时期,分别在小白鼠皮下及肌肉注射0.5mL国产及进口聚丙烯酰胺,并以生理盐水作空白对照,分期观察2种材料的组织病理学改变.结果:2种聚丙烯酰胺注入鼠皮下或肌肉内不引起急性或亚急性异物排斥反应,注入部位可很快形成纤维包膜将注入物包裹.结论:国产聚丙烯酰胺及进口产品具有相同且良好的生物相容性. AIM: To study the histocompatibility of polyacrylamide and to compare imported polyacrylamide with native one. METHODS: 32 Kunming species mice were divided into 3 groups. The 0.5 mL of imported and native polyacrylamide were separately injected into subcutaneous tissue and muscle in 4 different periods. The normal saline was used for the control. The tissues were obtained for pathological observation in different stages. RESULTS: Neither acute nor subacute foreign material reject reaction was found after the gel was injected in tissue. The gel was wrapped up rapidly by the fibrous capsule. CONCLUSION: Both the native and imported polyacrylamide shows the satisfied biocompatibility.
出处 《第四军医大学学报》 1999年第11期966-968,共3页 Journal of the Fourth Military Medical University
关键词 聚丙烯酰胺 纤维包膜 组织病理学 组织相容性 polyacrylamide fibrous capsule histology histopathology
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