摘要
目的研究医院真菌感染现状与耐药情况。方法各种临床标本经分离培养、鉴定和药敏试验。结果 122株真菌中,白色假丝酵母菌、热带假丝酵母菌分别占70.5%、14.8%;对11种常用抗真菌药物的耐药率由低到高排序依次为两性霉素B、制霉菌素、5-氟胞嘧啶、酮康唑、益康唑、氟康唑、咪康唑、克霉唑、伏立康唑、伊曲康唑、特比奈芬,分别为0、0、3.3%、8.2%、9.0%、23.8%、26.2%、26.2%、34.5%、47.5%、67.2%。结论临床上酵母样真菌感染以白色假丝酵母菌和热带假丝酵母菌较常见;真菌耐药菌株的检出率呈上升趋势,临床上必须重视真菌的检出和药敏试验。
OBJECTIVE To investigate the characteristics of fungus infection and drug resistance.METHODS The fungi were cultured,isolated and identified,and the drug sensitivity test was performed.RESULTS Among 122 strains of fungus,Candida albicans was the main species,according for 70.5%.Candida tropicalis accounted for 14.8%;The resistance rates to 11 antifungals were respectively as the followings：AMB 0.0%,NYS 0.0%,5FC 3.3%,KET（8.2%）,ECO（9.0%）,FLU（23.8%） MIC（26.2%）,CLO（26.2%）,VOR（34.5%）,ITC（47.5%） and TER（67.2%）.CONCLUSIONS The C.albicans and C.tropicalis are more common in clinical samples,and the positive rate of the drug resistant strains keeps an upward tendency.So the detection of fungi and the drug sensitivity test should be attached great importance in clinics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第6期1270-1271,共2页
Chinese Journal of Nosocomiology
关键词
真菌
药敏试验
分析
Fungi
Drug sensitivity tests
Analysis
