摘要
目的探讨蒙特利尔认知评估量表(MoCA)中文北京版用于帕金森病(PD)认知评估的可行性。方法分别用MoCA和简易智能状态检查量表(MMSE)对78例PD患者进行认知功能评估,分析评估结果。结果 PD患者MoCA与MMSE评分分别为(23.7±3.8)分和(27.7±2.3)分,MoCA评分明显低于MMSE,差异有统计学意义(P<0.05);Pearson相关分析显示,MoCA与MMSE总分显著相关(r=0.89,P<0.05)。在MMSE评定认知功能正常的患者中有50.7%MoCA评定有认知障碍。19例MMSE评分为30分患者的平均MoCA评分为(27.1±1.63)分,其中18例MoCA评分<30分。MoCA延迟回忆下降发生率明显高于MMSE记忆和回忆能力下降发生率。结论 MoCA与MMSE总分上有较好的相关性,MoCA用作PD认知筛查时敏感性高于MMSE,较MMSE更适合用于PD患者的认知障碍筛查。
Objective To investigate the feasibility of application of Montreal Cognitive Assessment Scale（MoCA） Chinese version to the assessment of global cognition in Parkinson＇s disease （PD）. Methods Seventy-eight PD patients were included. Their cognitive functions were assessed with MoCA and Mini-Mental State Examination（MMSE） and the results were analyzed and compared. Results Mean MoCA and MMSE scores standard deviation were 23.7±3.8 and 27. 7±2.3 respectively. MoCA scores were significantly lower than MMSE scores （P 〈 0.05） and there was a high correlation between the MMSE and the MoCA sores by Pearson correlation tests （r = 0.89,P 〈 0.05）. 50.7% of the PD patients with ＇normal＇ global cognition according to MMSE had cognitive impairment by MoCA. Nineteen cases with MMSE score 30 points had an average score（27.1 ± 1.63） points by MoCA,including 18 cases with MoCA score〈30 points. Conclusion MoCA and MMSE scores have a good correlation. The MoCA has higher sensitivity than the MMSE for cognitive assessment in PD patients. The MoCA is more suitable than the MMSE as a cognitive screening tool for PD patients.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2010年第9期771-773,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
国家自然科学基金(30870863,30801219)
广东省自然科学基金(7001198,06300979)
广东省医学科研基金(A2009038)
关键词
认知障碍
帕金森病
记忆障碍
回忆
蒙特利尔认知评估量表
简易智能状态检查量表
cognition disorders
Parkinson disease
memory disorders
mental recall
Montreal Cognitive Assessment Scale,Mini-Mental State Examination
