摘要
目的观察CT引导经皮穿刺腹腔神经丛阻滞对胃癌晚期疼痛的临床疗效。方法选取23例晚期胃癌伴有上腹部或腰背部疼痛患者,在CT引导下经皮穿刺行腹腔神经丛无水乙醇毁损性阻滞。观察并随访术前,术后第2周,术后第1、2、4、6个月患者的疼痛视觉模拟评分(VAS)并评估疗效,记录随访期间吗啡摄入量。结果 23例患者术后第2周临床治愈16例,显效3例,有效3例,无效1例,且术后不同时间患者的疗效间差异无统计学意义(P>0.05)。术后第2周～第6个月患者的疼痛VAS及吗啡摄入量均较术前显著降低,差异有统计学意义(P<0.01);且术后第2周～第6个月患者的疼痛VAS及吗啡摄入量呈逐渐增加趋势。结论 CT引导经皮穿刺腹腔神经丛阻滞可用于治疗胃癌晚期癌痛;但随着疼痛的复发,患者需要增加镇痛药物使用量。
Objective To observated the clinical efficacy of CT-guided celiac plexus block on pain of advanced gastric cancer.Methods 23 patients with advanced gastric cancer associated with more abdominal and back pain patients,were carried on neurolytic block with dehydrated ethanol celiac plexus CT-guided.To observe and follow-up preoperative,after the first 2 weeks,and the after 1,2,4,6 months and to assess the pain VAS,recording oral morphine during the drug usage.Results 23 patients,clinical cure in 16 cases （69.6%）,excellent in 3 cases （13.0%）,effective in 3 cases （13.0%）,ineffective in 1（4.4%）,markedly effective rate was 82.6%.There is no significant differences postoperative after each time point.The first 2 weeks to the first six months when the VAS when compared with preoperative reduced （P0.01）,The first 2 weeks to the first six months when the VAS showed a gradual upward trend in drug intake of morphine in the time,when compared with preoperative reduced（P0.01）.Conclusion CT-guided percutaneous neurolytic celiac plexus block can be used for the treatment of advanced gastric cancer pain.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第26期2928-2930,共3页
Chinese General Practice
基金
浙江省医药卫生科学研究基金(2005B153)
