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关于优化降糖治疗——“2退1”策略在预混胰岛素控制不佳患者中的应用 被引量：4

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摘要 10名成人中就会有1例糖尿病患者；10例糖尿病患者中只有3例经过治疗后血糖控制达标（HbA1c〈6．5％），这是我国内分泌医生所面对的现状和挑战。因此，优化糖尿病治疗策略以提高患者的降糖达标率刻不容缓。
作者 冯凭
机构地区 天津医科大学总医院内分泌科
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2010年第9期714-715,共2页 Chinese Journal of Diabetes
关键词 糖尿病 2型 预混胰岛素 降糖
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献4

  • 1Rizvi AA. The use of premixed insulin analogues in the treatment of patients with type 2 diabetes mellitus: advantages and limitations. Insulin, 2007,2 : 68 -79.
  • 2Hammer H, Klinge A. Patients with type 2 diabetes inadequately controlled on premixed insulin: effect of initiating insulin glargine plus oral antidiabetic agents on glycaemie control in daily practice. Int J Clin Praet,2007,61 : 18.
  • 3卜石,郭晓蕙,杨文英,卢桂芝,杨兆军,任婷婷,高妍.预混胰岛素转为基础胰岛素联合口服降糖药治疗方案的2型糖尿病患者的临床特征分析[J].中华医学杂志,2007,87(44):3115-3118. 被引量：51
  • 4杨文英.预混胰岛素治疗血糖控制不佳的2型糖尿病患者转换使用甘精胰岛素联合口服药治疗后血糖达标的人群特征分析[J].湘雅论坛壁报,2010,4.

二级参考文献10

  • 1Global Guideline for Type 2 diabetes: recommendations for standard, comprehensive, and minimal care. Diabet Meal, 2006, 23:579-593.
  • 2Shank ML, Del Prato S, DeFronzo RA. Bedtime insulin/daytime glipizide. Effective therapy for sulfonylurea failures in NIDDM. Diabetes, 1995,44 : 165-172.
  • 3Riddle MC. Evening insulin strategy. Diabetes Care, 1990, 13: 676-686.
  • 4Taskinen MR, Sane T, Helve E, et aL Bedtime insulin for suppression of overnight free-fatty acid, blood glucose, and glucose production in NIDDM. Diabetes, 1989,38:580-588.
  • 5Heinemann L, Linkeschova R, Rave K, et al. Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo. Diabetes Care, 2000,23:644-649.
  • 6Riddle MC, Rosenstock J, Gefich J. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care, 2003,26: 3080-3086.
  • 7Raskin P, Allen E, Hollander P, et al. Initiating insulin therapy in type 2 diabetes: a comparison of biphasic and basal insulin analogs. Diabetes Care, 2005,28:260-265.
  • 8Janka HU, Plewe G, Riddle MC, et al. Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes. Diabetes Care, 2005, 28:254-259.
  • 9Turner RC, Cull CA, Frighi V, et al. Glycemic control with diet, sulfonylurea, mefformin, or insulin in patients with type 2 diabetes meUitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. JAMA, 1999,281:2005-2012.
  • 10Davidson JA, Garber A J, DiMarchi RD, et al. New advances in insulin treatment of diabetes: overcoming barriers. Endocr Practice, 1997,3:371-384.

共引文献50

同被引文献32

  • 1李光伟.对2型糖尿病β细胞功能衰竭和胰岛素治疗的思考——给2型糖尿病病人一个更为美好的未来[J].国外医学（内分泌学分册）,2004,24(4):271-273. 被引量：52
  • 2杨文英.预混胰岛素治疗血糖控制不佳的2型糖尿病患者转换使用甘精胰岛素联合口服药治疗后血糖达标的人群特征分析[J].湘雅论坛壁报,2010,4.
  • 3McKeage k, Goa KL. Insulin glargine: a review of its therapeutic use a long - acting agent for the management of type 1 and 2 diabetes mellitus. Drugs 2001 ;61 ( 11 ) :1599 - 1624.
  • 4Rizvi AA i et al. The Use of Premixed Insulin Analogues in the Treatment of patients with Type 2 DiabetesMellitus: Advantagesand Limitations. Insulin 2007 ;2:68 - 79.
  • 5Davidson JA, DiMarchi RD, et al. New advances in insulin treatment of the diabetes: overcoming barriers. Endocr Practice 1997 ;3:371 - 384.
  • 6Hammer H, Klinge A. Patients with type 2 diabetes inade- quately controlled on premixed insulin: effect of initiating insulin glargine plus oral antidiabetic agents on glycaemic control in daily practice. Int J Pract 2007;61(12) :2009 -2018.
  • 7Brunton S.Insulin regimens for type 2 diabetes mellitus[J].Fam Pract,2006,55:S10-17.
  • 8UK Prospective Diabetes Study Group:Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patiens with type 2 diabetes (UKPDS 33)[J]. Lancet,1998,352:857.
  • 9卜石,郭晓蕙,杨文英,卢桂芝,杨兆军,任婷婷,高妍.预混胰岛素转为基础胰岛素联合口服降糖药治疗方案的2型糖尿病患者的临床特征分析[J].中华医学杂志,2007,87(44):3115-3118. 被引量：51
  • 10Kim MK,Suk JH,Kwon MJ,et al.Nateglinide and acarbose for postprandial glucose control after optimizing fasting glucose with insulin glargine in patients with type 2 diabetes[J].Diabetes Res Clin Pract,2011,92(3):322-328.

引证文献4

二级引证文献2

中国糖尿病杂志
2010年 第9期

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