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真菌感染性食道炎病原学特点及药敏分析 被引量:2

Characteristics of Fungi and Drug Susceptibility of Esophagitis Infected with Fungi
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摘要 目的观察真菌感染性食道炎病原学特点及药敏结果,指导临床用药。方法从116例真菌感染的食道炎患者中,取标本进行真菌检测和药敏试验。结果共分离出118株真菌,以白色假丝酵母菌、热带假丝酵母菌和克柔假丝酵母菌居多,分别为31.36%、27.97%和14.41%;胃炎占62.71%,胃溃疡占11.02%,十二指肠炎占16.10%,十二指肠溃疡占10.17%;真菌对制霉菌素和两性霉素B药物敏感性好,但对唑类药物敏感性不一。结论真菌感染性食道炎患者真菌鉴定及药敏试验,对临床用药具有重要的指导意义。 OBJECTIVE To investigate the clinic characteristics of fungi and and their drug susceptibility,and to direct the clinical use of drugs.METHODS The clinical data were collected from 116 esophagitis infected with fungi.The fungi were identified and their drug-resistance were analyzed.RESULTS A total of 118 fungi were isolated.The 3 dominant fungal species identified were Candida albicans accounting for 31.36%,C.tropicalis accounting for 27.97%,and C.krusei accounting for 14.41%.Gastritis accounted for 62.71%,gastric ulcer 11.02%,duodenitis 16.10%,duodenal ulcer 10.17%.They showed good drug-sensitivity to nystatin and amphotericin B,but not to the azole drugs.CONCLUSION It has important guiding significance to identify fungal and test drug-resistance in clinical application of drugs.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2010年第13期1986-1987,共2页 Chinese Journal of Nosocomiology
关键词 感染 真菌 白色假丝酵母菌 食道炎 Infection Fungi Candida albicans Esophagitis
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  • 1李益农,陆星华.消化内镜学[M].北京:北京科学出版社,2004:709-717.
  • 2陈浩军,林树洪,邝杰思,等.真菌性食管炎临床和内镜表现与治疗[J].现代消化及介入治疗,2012,17(3):168-169.
  • 3Kliemann DA, Antonello VS,Severo I,C. Saecharomyces ccrevisiae ocsophagitis in a patient with oesophageal carcinoma[J]. J Infect Dev Ctries,2011,5(6) :493 -495.
  • 4Falagas ME, Grammatikos AP, Michalopeulos A. Potential of old- generation antibiotics to address current need for new antibiotics [J]. Anti Infect Ther,2008,6(5) :593 -600.
  • 5Purdy JK,Appelman HD,McKenna BJ. Sloughing esophagitis is associated with chronic debilitation and medications that injure the e- sophageal mucosa[ J]. Mod Pathol,2012,25(5) :767 - 775.
  • 6Sievert DM, Rudrik JT,Patel JB. Vancomycin resistant Staphyloccus aureus in the United States, 2002 - 2006 [ J ]. Clinical Infectious Diseases ,2008,46(5 ) :668 - 674.
  • 7Pahl R,Brunke G,Steubesand N. IL-1β and ADAM17 are central regulators of β - defensin expression in Candida esophagitisa [J]. Am J Physiol Gastrointest Liver Physiol,2011,300 (4) :547 - 553.
  • 8Zhu X, Wang M, Cramp CH. An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice [J]. Am J Physiol Gastroinlest Liver Physiol, 2009,297 (3) :550 -558.
  • 9朱大磊,车筑萍,许良璧.真菌性食管炎95例临床分析[J].临床消化病杂志,2009,21(1):56-58. 被引量:8
  • 10陈忠华,何庆玲,陈杨.抑酸和促动力药物对真菌性食管炎的临床疗效和病理转归分析[J].重庆医科大学学报,2009,34(6):769-771. 被引量:4

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