摘要
[目的]探讨分形维参数及异质性参数对鉴别乳腺良恶性病变的诊断价值。[方法]对经病理证实的20例乳腺浸润性导管癌及20例乳腺纤维腺瘤的数字钼靶图像进行分析,对肿瘤边界的分形维参数Df和肿瘤内部的异质性参数H进行定量评估。[结果]乳腺浸润性导管癌和纤维腺瘤的分形维参数Df值分别为1.204、1.135,有显著性差异(P<0.001);异质性参数H值分别为0.444、0.237,有显著性差异(P<0.001)。[结论]应用分形维参数及肿瘤内部异质性参数对鉴别乳腺良恶性肿瘤有一定的诊断价值。
[Purpose] To investigate the fractal dimension and degree of heterogeneity in differential diagnosis for breast tumors.[Methods] The mammography imaginges of 20 cases with infiltrating ductal carcinoma and 20 cases with fibroadenoma pathologically proven were analyzed.Two parameters,the fractal dimension（Df） in border of tumor and the degree of heterogeneity H in inner tumor,were computed numerically.[Results] The fractal dimension value in breast infiltrating ductal carcinoma,and in fibroadenoma was 1.204 and 1.135 respectively with significant difference（P〈0.001）,and heterogeneity value was 0.444 and 0.237 respectively（P〈0.001）.[Conclusion] The analyses based on fractal dimension and degree of heterogeneity is valuable for differention between malignant and benign breast tumors.
出处
《肿瘤学杂志》
CAS
2010年第3期171-174,共4页
Journal of Chinese Oncology
基金
国家863计划资助项目(2006AA02A404)
国家自然科学基金资助项目(30770629)
广东省医学科研基金资助项目(A2005251)
