摘要
目的观察止汗散治疗肿瘤患者多汗症的疗效。方法45例合并多汗症的肿瘤患者,随机分为试验组24例和对照组21例,分别予止汗散与安慰剂敷脐,采用皮肤电阻仪测量用药前后各部位皮肤电阻的变化,并根据中医常见症状、体征分级积分表观察用药前后证候以及卡氏功能量表(KPS)的变化。结果试验组前额、前胸、掌心部位皮肤电阻用药前后及与对照组比较差异均有统计学意义(P<0.01);用药后自汗、盗汗、口干、手足心热、身热、畏寒肢冷、喘憋气短、太息等症状明显改善(P<0.05,P<0.01)。2组治疗后KPS评分均上升,但差异无统计学意义(P>0.05)。结论止汗散敷脐治疗肿瘤患者多汗症疗效确切。
Objective To observe the therapeutic effect of the traditional Chinese medicine （TCM） Sweat Reduction Powder on hyperhidrosis in neoplasms. Methods Forty-five neoplasms patients with hyperhidrosis were divided into two groups randomly, 24 cases were selected as experimental group （Sweat Reduction Powder treatment group）and 21 patients were selected as control group（placebo treatment group）. The change of skin electrical resis tance was tested and compared before and after treatment. According to TCM symptoms and signs, the clinical manifestations were then matched against the scoring table, as well as the score of KPS to evaluate any changes in the quality of life for the patients. Results Three parts of skin electrical resistance （ forehead, prothroax, palm centre） variance before and after treatment in experimental group were significant higher than control group （ P 〈 0.01 ）. There were also improvement of symptoms in experimental group, which defined in TCM as spontaneous perspiration, night sweating, dry mouth, feverish sensation over hand foot centers and body, aversion to cold etc （ P 〈 0.05 or P 〈 0.01 ）. The KPS scoring increased in both two groups, while no statistical difference （ P 〉 0.05 ）. Conclusion It proved to be effective when applying TCM powder patch in the navels of patients with hyperhidrosis in neoplasms.
出处
《疑难病杂志》
CAS
2010年第3期168-170,共3页
Chinese Journal of Difficult and Complicated Cases
基金
"十一五"国家科技支撑计划项目(No.2007BAI10B01-101)
关键词
皮肤电阻
多汗症
中医外治法
牛活质量
Skin electrical resistance
Hyperhidrosis
External therapy of traditional Chinese medicine
Living quality
