期刊文献+

过敏性结膜炎药物治疗研究进展 被引量:13

暂未订购
导出
摘要 过敏性结膜炎是一类常见的眼表过敏性疾病,其主要由Ⅰ型及Ⅳ型变态反应引起。药物是本类疾病的主要治疗手段,局部用药可为病变部位提供更高的药物浓度,起效更快、更好,且可避免全身用药引起的副作用。近来局部治疗过敏性结膜炎的药物种类明显增多,给临床治疗提供了更多选择。这些药物包括抗组胺药、血管收缩剂(减少充血剂)及其复方制剂、肥大细胞稳定剂、双效抗组胺药、非甾体抗炎药和糖皮质激素,其中0.2%奥洛他定滴眼液是首个每日1次的双效抗组胺药。因此进一步开发长效、高效和耐受性良好的抗过敏滴眼剂对于提高患者用药的方便性和依从性意义重大。同时,对于局部使用某些免疫抑制剂治疗严重的顽固性的春季角结膜炎和特应性角结膜炎的有效性和安全性的评价还需要进行多中心大样本的临床观察。
出处 《天津药学》 2009年第5期67-71,共5页 Tianjin Pharmacy
  • 相关文献

参考文献34

  • 1Hannouche D,Hoang-Xuan T.Allergic conjunctivitis.In:Hosng Xuan T,Baudouin C,Creazot-Garcher C,eds.Inflammatory diseases of the conjunctiva.New York:Stettgart,2001,53.
  • 2Calange M.Classification of ocular atopic/allergic disorders and conditions:an unsolved problem.Acta Opthalmol Stand Supple,1999,228:10.
  • 3程勤益,邹俊.变应性结膜炎的药物治疗[J].世界临床药物,2007,28(7):398-403. 被引量:3
  • 4黄世杰.第二代抗组胺药治疗过敏性结膜炎的疗效和耐受性[J].国外医学(药学分册),2005,32(4):269-271. 被引量:5
  • 5Bielory L,Lien K W,Bigelsen S.Efficacy and tolcrability of newer Antihistamines in the treatment of allergic conjunctivitis.Drug,2005,65 (2):215.
  • 6Fujishima H,Fukagawa K,Takano Y,et 02.The early efficacy of topical levocabastine in patients with allergic conjunctivitis.Allergol Int,2006,55(3):301.
  • 7Takamura E,Nomura K,Fujishima H,et al.Efficaey of levoeabaatine hydrochloride ophthalmic suspension in the conjunctival allergen challenge test in Japanese subjects with seasonal allergic conjunctivitis.Allergol Int,2006,55 (2):157.
  • 8Endre L.The prompt effect of emedastine eye drop and the safety of its permanent use in children suffering from acute seasonal allergic conjunctivitis.On,Hetil,2007,148 (6):251.
  • 9Adefule-Ositelu A O,Onakoya A O,Olasimbo O O,et al.A Clinicopatholo-gical analysis of the efficacy of lodoxamide 0.1% eye drops on the conjunctiva of patients with vernal kerateconjunctivitis seen at Guinness Eye Centre,Lagos University Teaching Hospital.Niger Poatgrad Med J,2006,13(1):35.
  • 10Horak F,StUbner P,Zieglmayer R,et al.Onset and duration of action of ketotifen 0.025% and emedastine 0.05% in seasonal allergic conjunctivitis:efficacy after repeated pollen challenges in the Vienna challenge chamber.Clin Drug Investig,2003,23(5):329.

二级参考文献10

  • 1Bleik JH, FRCS, Tabbara KF. Topical Cyclosporine in vernal keratoconjunctivitis. Ophthalmology, 1991, 98: 1679~ 1684
  • 2Akpek EK, Hasdiripi H, Christer WG, et al. A randomized trial of low dose, topical mitomycin C in the treatment of severe vernal keratoconjunctivitis. Ophthalmology, 2000, 107 (2): 263~269
  • 3Nishiwaki - Dantas MCM, Dantas PE, Pezzutt S, et al. Surgical resection fo giant papillae and autologous conjunctival graft in patients with severe vernal keratoconjunctivitis and giant papillae. Ophthal Plast Reconstr Surg, 2000, 16 (6): 438~442
  • 4BenEzra D, Pe'er J, Brodsky M, et al. Cyclosporine eyedrops for the treatment of severe vernal keratoconjunctives. Am J Ophthalmol,1986, 101 (3): 278~282
  • 5Hikita N, Lopez JS, Chan CC, et al. Use o topical FK506 in a corneal graft rejection model in Lewis rats. Invest Ophthalmol Vis Sci,1997, 38 (5): 901~909
  • 6Kino T, Hatanaka H, Miyata S, et al. FK506, a novel immunosuppressant isolate from a Streptomyces Ⅱ. immunosuppressive effect of FK506 in vitro. J Antibiot, 1987, 9:1256~1265
  • 7Leonardi A, DeFranchis GF, et ald. Effects of cyclosporin A on human conjunctival fibroblasts. Arch Ophthalmol, 2001, 119 (10):1512~1517
  • 8W. Parys,S. Blockhuys,M. Janssens. New trends in the treatment of allergic conjunctivitis[J] 1992,Documenta Ophthalmologica(4):353~360
  • 9林跃生,陈家祺,刘永民,周世友,谢汉平,王敏华.眼表重建术后局部应用FK-506的初步临床观察[J].眼科新进展,2000,20(4):249-251. 被引量:5
  • 10谢汉平,陈家祺,林跃生,刘永民,叶成添.FK506滴眼液联合角膜移植术治疗复发性蚕蚀性角膜溃疡[J].中华眼科杂志,2002,38(1):13-15. 被引量:25

共引文献23

同被引文献91

引证文献13

二级引证文献114

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部