期刊文献+

8885例早孕人工流产中葡萄胎发生情况调查

Survey of Hydatidiform Mole Incidence among 8885 Patients after Artificial Abortion
原文传递
导出
摘要 目的:探讨葡萄胎发病率及其相关因素。方法:根据8885例早期人工流产患者术后病理结果筛选出葡萄胎患者,对其进行血β-hCG随访及相关检查,应用统计学分析方法,寻找临床出现葡萄胎表现之前的葡萄胎发生的可能指征及其影响因素。结果:8885例早孕人工流产患者中有14例发生葡萄胎,发病率为1.57‰;稽留流产患者葡萄胎发病比例(0.78%)显著高于正常妊娠者(0.10%);葡萄胎患者与正常妊娠者术后转经时间无差异。结论:生育旺盛年龄妇女是发生葡萄胎的主要人群,人流患者(特别是稽留流产患者)的绒毛组织做常规病理学检查可提高葡萄胎的检出率。 Objective: To explore the rate of hydatidiform mole and its correlative factors through the survey of 8 885 patients after artificial abortion in Shanghai. Methods: The cases of hydatidiform mole were determined by the analysis of pathology tests of these patients. Then the 13-hCG and other related tests were carded out. The rate of hydatidiform mole without clinical symptom and its correlative information were collected and analyzed with statistics methods. Results: Fourteen cases of hydatidiform mole were determined among 8 885 patients received artificial abortion. The incidence rate was 1.57‰. The missed abortion patients showed higher risk of developing hydatidiform mole (0.78%) than normal gestation women (0.10%). Conclusion: More cases of hydatidiform mole are observed in women at reproductive active age than other age groups.
出处 《生殖与避孕》 CAS CSCD 北大核心 2009年第10期693-695,共3页 Reproduction and Contraception
关键词 葡萄胎 人工流产 绒毛病理 hydatidiform mole artificial abortion pathology of villus
  • 相关文献

参考文献7

  • 1宋鸿钊.全国23省市自治区200余万妇女葡萄胎发病率调查[J].中华医学杂志,1980,60:641-644.
  • 2Wolfberg AJ, Feltmate C, Goldstein DP, et al. Low risk of relapse after achieving undetectable HCG levels in women with complete molar pregnancy. Obstet Gynecol, 2004, 104 (3):551-4.
  • 3万小云.葡萄胎的研究进展[J].现代妇产科进展,2008,17(1):4-7. 被引量:21
  • 4Garner EI, Goldstein DP, Feltmate CM, et al. Gestational trophoblas-tic disease. Clin Obstet Gynecol, 2007, 50(1): 112-22.
  • 5程丽村,赵欣荣,俞青.绒毛染色体检测在分析稽留流产原因中的应用[J].中国优生与遗传杂志,2006,14(2):27-27. 被引量:28
  • 6张惜阴(主编).实用妇产科学.2版.北京:人民卫生出版社,2007:732.
  • 7Chakrabarti BK, Mondal NR, Chatterjee T. Gestational trophoblastic tumor at a tertiary level cancer center: a retrospective study. J Reprod Med, 2006, 51(11):875-8.

二级参考文献17

  • 1陈雪,胡娅莉.自然流产的遗传因素及诊断[J].国外医学(妇产科学分册),2004,31(6):340-343. 被引量:14
  • 2Garner EI, Goldstein DP, Feltmate CM, et al. Gestational trophoblastic disease [ J ]. Clin Obstet Gynecol, 2007,50 : 112-122
  • 3Garner EI, Lipson E, Bernstein MR, et al. Subsequent pregnancy experience in patients with molar pregnancy and gestational trophoblastic tumor [ J ]. J Reprod Med, 2002,47:380-386
  • 4Fulop V, Mok SC, Gati I, et al. Recent advances in molecular biology of gestational trophoblastic diseases. A review [ J ]. J Reprod Med, 2002,47 : 369-379
  • 5Genest DR, Ruiz RE, Weremowicz S, et al. Do nontriploid partial hydatidiform moles exist? A histologic and flow cytometric reevaluation of nontriploid specimens [J].J Reprod Med ,2002,47:363-368
  • 6Judson H, Hayward BE, Sheriden E, et al. A global disorder of imprinting in the human female germ line [ J ]. Nature,2002,416:539-542
  • 7Fisher RA, Hodges MD,Rees HC,et al. The maternally transcribed gene p57 (KIF2) (CDNK1C) is abnormally expressed in both androgenetic and biparental complete hydatidiform moles [ J ]. Hum Mol Genet, 2002,11 : 3267- 3272
  • 8Thaker HM ,Berlin A,Tycko B ,et al. Immunohistochemistry for the imprinted gene product IPL/PHLDA2 for facilitaring the differential diagnosis of complete hydatidiform mole [ J ]. J Reprod Med,2004,49:630-636
  • 9Fisher RA, Hodges MD, Newlands ES. Familial recurrent hydatidiform mole: a review [ J ]. J Reprod Med ,2004 ,49 : 595-601
  • 10Bestor TH, Bourchis D. Genetics and epigenetics of hydatidiform mole [ J ]. Nat Genet,2006,38:274-276

共引文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部