期刊文献+

肾素抑制剂阿利吉仑及其临床研究进展 被引量:6

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出处 《上海医药》 CAS 2009年第11期517-520,共4页 Shanghai Medical & Pharmaceutical Journal
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  • 2Wood JM. Structure - based design of aliskiren, a novel orally effective renin inhibitor. Biochem [J]. Biophys Res Commun, 2003,308(4) : 698 -705.
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  • 4Vaidyanathan S, Valencia J, Kemp C, et al. Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide ( HCTZ ) and ramipril in healthy volunteers [J]. Int J Clin Pract,2006,60(11) : 1343 -1356.
  • 5Vaidyanathan S,Camenisch G, Schuetz H, et al. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P- Glycoprotein in the disposition of aliskiren [J]. J Clin Pharmacol, 2008,48 ( 11 ) : 1323 - 1338.
  • 6Stanton A, Jensen C, Nussberger J, et al. Blood pressure lowering in essential hypertension with an oral rennin inhibitor, aliskiren [J]. Hypertension,2003,42(6) : 1137 - 1143.
  • 7Gradman A.H.,Schmieder R.E.,Lins R.L.,M.P. Bedigian,刘文秀.新型口服肾素抑制剂阿利吉仑对高血压患者有剂量依赖性抗高血压作用及与安慰剂相当的耐受性[J].世界核心医学期刊文摘(心脏病学分册),2005,0(8):35-36. 被引量:23
  • 8Oh BH, Mitchell J, Herron JR, et al. Aliskiren, an oral renin inhibitor, provides dose - dependent efficacy and sustained 24 - hour blood pressure control in patients with hypertension [ J ]. J Am Coll Cardiol,2007,49( 11 ) : 1157 - 1163.
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  • 5Azizi M, Webb R, Nussberger J, et al. Renin inhibition with aliskiren: where are we now, and where are we going?[J]. J Hypertens, 2006, 24(2): 243-256.
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  • 7Musini VM, Fortin PM, Bassett K, et al. Blood pressure lowering efficacy of renin inhibitors for primary hypertension: a Cochrane systematic review[J]. J Hum Hypertens, 2009, 23(8): 495-502.
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