摘要
[目的]观察高原地区不同海拔高度养路工人的细胞免疫水平。[方法]对海拔2800m、3500m、4000m3个海拔高度的养路工人进行T细胞亚群CD3、CD4、CD8、CD4/CD8和白细胞(WBC)、淋巴细胞(LY)检测。[结果]海拔4000m养路工人的CD3、CD4、CD8、CD4/CD8、WBC值增高最为明显(分别为85.46±7.18、47.25±8.62、33.25±9.55、1.58±0.69、6.94±1.65),而2800m则无明显增高。3个海拔高度工人的CD3、CD4、CD8、CD4/CD8和WBC值比较差异有统计学意义(P<0.01),各项值随海拔增高而增高(以CD3更为明显)。LY各组间比较,差异无统计学意义(P>0.05)。[结论]高原缺氧影响人体生理功能和免疫功能,因此在高原地区,做好体力劳动者的劳动和卫生保障工作是十分必要的。
[Objective] To observe the cellular immunity level of road maintenance workers working at different altitude plateau region.[ Methods] Road maintenance workers working at 3 different altitudes,namely 2 800 m,3 500 m,and 4 000 m,were selected as subjects.Their T-lymphocyte subsets CD3,CD4,CD8,CD4/CD8 and white blood cel（lWBC）,as well as lymphocytes（LY）were detected.[ Results] CD3,CD4,CD8,CD4/CD8,and WBC values in workers at 4 000 m were increased most obviously,the values were 85.46±7.18,47.25±8.62,33.25±9.55,1.58±0.69,and 6.94±1.65,respectively.Those values were not significantly increased in worker at 2 800 m.The values of all detected indices but LY in the three altitude groups showed significant difference（P 〈 0.01）,and showed an increasing tendency with the altitude,in which CD3 was the most obvious one.[Conclusion] The low oxygen environment at high altitude affects on workers＇physiological function and immune function.To improve the labor and health protection for workers at the plateau region is very necessary.
出处
《环境与职业医学》
CAS
北大核心
2009年第5期498-499,共2页
Journal of Environmental and Occupational Medicine
基金
交通部西部交通建设科技项目(编号:200631800051)
关键词
不同海拔
T细胞亚群
白细胞
淋巴细胞
differernt altitudes
T cell subpopulation
white blood cell
lymphocyte
