摘要
目的:探讨儿童肾脏疾病血清的免疫球蛋白、补体检测诊断意义。方法:利用液相免疫化学原理,检测239例肾脏疾病患儿免疫球蛋白(IgG、IgA、IgM)、补体(C3、C4)的含量,以30例健康儿童为对照,进行对比分析。结果:患儿急性肾炎和肾病综合症IgG含量低于正常对照组,有显著性差异(P<0.01);肾病综合症IgM,紫癜性肾炎IgA,狼疮性肾炎IgG、IgA、IgM明显高于对照组,有显著性差异(P<0.01)。肾脏疾病各组C3、C4均下降,狼疮性肾炎C3、C4与对照组比较有显著性差异(P<0.05)。结论:评估肾脏疾病的免疫球蛋白和补体的检测,为临床提供早期诊断依据。
Objective： To explore the value of immune serum globulin, complement in diagnosis of kidney disease in children. Methods： Principle of the use of liquid - phase immunochemistry to detect 239 cases of kidney disease in children with immunoglobulin （ IgG, IgA, IgM ）, complement （ C3, C4 ） levels of 30 healthy children as controls, were analyzed. Results： Children with acute nephritis and nephrotic syndrome IgG content of lower than normal control group, the difference was significant （P 〈0. 01）; nephrotic syndrome IgM, purpuric nephritis IgA, lupus nephritis IgG, IgA, IgM significantly the control group, the difference was significant （P 〈 0. 01 ）. Kidney disease in each group C3, C4 decreased, lupus nephritis C3, C4 compared with the control group were significantly different （ P 〈 0.05 ）. Conclusion： Assessment of renal disease immunoglobulin and complement testing can help to have early diagnosis of kidney disease.
出处
《中国卫生检验杂志》
CAS
2009年第7期1614-1614,1620,共2页
Chinese Journal of Health Laboratory Technology
关键词
肾脏疾病
患儿
免疫球蛋白
补体
Kidney disorders
Children
Immunoglobulin
Complement
