摘要
目的探讨血管栓塞患者血浆溶血磷脂酸(LPA)和D-二聚体水平变化的临床意义。方法选择肺动脉栓塞9例,下肢静脉栓塞26例,心肌梗死38例,脑血栓79例;同时测定60例健康者为对照组。分别测定各组治疗前、后LPA和D-二聚体。结果血管栓塞各组治疗前LPA值分别为(3.02±0.76)μmol/L、(2.71±0.84)μmol/L、(3.80±0.61)μmol/L、(3.60±1.51)μmol/L;D-二聚体各组均为阳性。对照组LPA均值为(1.84±0.67)μmol/L;D-二聚体为阴性。血管栓塞各组与对照组比较,LPA差异有统计学意义(P<0.01),经治疗后LPA与对照组差异也有统计学意义(P<0.01)。结论血浆LPA、D-二聚体作为体内凝血和血栓形成早期的分子标注物有重要临床诊断价值。
Objective To investigate the clinical value of LPA and D diner for the changes in patients with vascular chmoembolization. Methods The patients were divided into four groups： 9 cases of lung arterial embolism, 26 cases of leg venous thromboembolism,38 cases of myocardial infarcltion and 79 cases of CI while the control group was 60 cases of healths. LPA and D-dimer were detected respectively before and after treatment in the groups. Resuits Before treated, LPA for the therapeatic groups was （3.02± 0. 76）μmol/L, （2. 71 ± 0. 84）μmol/L, （3.8 ±0.61）μmol/L and （3.6± 1.5）μmol/L;D-dimer was positive for the groups ; while the LPA for the control group was （1.84 ±0.67）μmol/L, and the D dimer was negative. The therapeatil groups were significantly different from that of the control goup（P〈0.01）. Conclusion There was of statistic importance for the detection of LPA and D dimer used for the marker in the earlier period of thrombosis.
出处
《检验医学与临床》
CAS
2009年第13期1034-1034,1036,共2页
Laboratory Medicine and Clinic
