摘要
目的比较阿立哌唑与利培酮对女性精神分裂症患者生活质量的影响。方法对符合《中国精神障碍分类与诊断标准》第3版(CCMD-3)精神分裂症诊断标准的70例女性患者随机分为阿立哌唑组和利培酮组治疗6个月,用阳性症状与阴性症状量表(PANSS)评定精神症状,用生活质量量表(QOL)对2组治疗前、治疗后进行评定分析。结果阿立哌唑与利培酮对精神分裂症的阳性症状、阴性症状的改善相似,PANSS 2组间评分差异无统计学意义。阿立哌唑组QOL各领域除精神支柱外均明显改善,在生活领域、心理领域、独立性领域、社会关系领域较利培酮组改善显著。结论阿立哌唑组更能改善女性患者的生活质量,有利于患者重返社会。
Objective To compare the effects of aripiprazole and risperidone on the life quality of female schizophrenics. Methods Seventy schizophrenics （met the criteria of CCMD-3 for female schizophrenia） were randomly divided into aripiprazole group （n=35）and risperidone group （n=35）, treated for six months,and were assessed with PANSS and QOL before treatment and at the end of 6th month of post-treatment. Results Aripiprazole and risperidone had similar effects on positive and negative symptoms of schizophrenia. There was no significant difference between the score of PANSS in two groups. Aripiprazole group had a better result in physical,psychological,level of independence, social relations than risperidone group. Conclusion Aripiprazole is better for improving the life quality and beneficial to female patients returning to society.
出处
《中国实用神经疾病杂志》
2009年第9期13-15,共3页
Chinese Journal of Practical Nervous Diseases
关键词
阿立哌唑
利培酮
女性
生活质量
Aripiprazole
Risperidone
Female
Quality of life
